Usefulness and feasibility of repeated tail artery cannulations in the rat

Kosuke Kumagai, Terushige Toyooka, Yohei Otsuka, Masahiro Horikawa, Kentaro Yamada, Arata Tomiyama, Satoru Takeuchi, Koichi Kurihara, Kojiro Wada

Research output: Contribution to journalArticlepeer-review


Rat ventral caudal artery (VCA, tail artery) cannulation for blood pressure monitoring and blood sampling is essential for maintaining consistent procedures in rat models. Double or triple insults are sometimes necessary, but repeated VCA cannulations have not been compared with repeated femoral artery cannulations. In addition, the collateral system for resistance to ischemia in the rat tail is unclear. Our present study revealed that repeated VCA cannulations on different days was a better technique than repeated femoral artery cannulations in terms of surgical time, postsurgical weight loss and ischemic complications. Furthermore, the lateral caudal arteries and the segmental anastomosing vessels were important for resistance to ischemic complications after VCA occlusion.

Original languageEnglish (US)
Pages (from-to)230-233
Number of pages4
JournalBlood Pressure Monitoring
Issue number3
StatePublished - Jun 1 2021


  • femoral artery
  • rat
  • repeated cannulation
  • tail artery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Assessment and Diagnosis
  • Advanced and Specialized Nursing
  • Internal Medicine


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