Uterine and fetal hemodynamics and fetal cardiac function in early pregnancy

P. Jouppila, K. Makikallio-Anttila, J. Rasanen, A. Tekay

Research output: Contribution to journalConference articlepeer-review


Our results in a longitudinal study protocol at 5, 7, 8 and 10 weeks demonstrate that in normal pregnancies the arterial signals of the yolk sac circulation disappear and umbilicoplacental circulation simultaneously increases between 8 and 10 weeks. Spiral artery impedance decreases between 5 and 7 weeks. In the uterine and arcuate arteries a decrease in impedance and an increase in blood flow velocities occurs after 8 week. Vaginal bleeding with or without subchorionic hematoma is associated with an increased radial artery impedance at 7 weeks of pregnancy. Miscarriage could, however, not be predicted by means of Doppler ultrasonography. Significant improvement in the diastolic function of fetal heart between 6 and 7 weeks is accompanied by increased mean velocities across inflow and outflow tracts. Appearance of biphasic inflow pattern is associated with significant change in the systolic function of heart between 8 and 9 weeks. Atrioventricular valve recurgitation is a common finding at 10 week. These findings suggests that the first trimester of human pregnancy represents great transitional changes at all levels of fetal and placental hemodynamics.

Original languageEnglish (US)
Pages (from-to)A204
JournalUltrasound in Medicine and Biology
Issue numberSUPPL. 2
StatePublished - 2000
Externally publishedYes
EventThe 9th Congress of World Federation for Ultrasound in Medicine and Biology - Florence, Italy
Duration: May 6 2000May 10 2000

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics


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