TY - JOUR
T1 - Uveal melanoma
T2 - Case report of extension through the optic nerve to the surgical margin in the orbital apex
AU - Chess, J.
AU - Albert, D. M.
AU - Bellows, A. R.
AU - Dallow, R.
PY - 1984
Y1 - 1984
N2 - An unsuspected uveal melanoma arising in a phthisical eye extended through the optic nerve to the surgical margin in the orbital apex without involvement of other orbital structures. Step sections showed the continuous extension through the nerve. Factors likely to predispose to optic nerve extension include epithelioid cell type, large tumour size, peripapillary involvement, and glaucoma. Optic nerve extension carries the risks noted with orbital extension of intraocular tumour, but may in addition lead more directly to intracranial invasion, including a chiasmal syndrome. The role of exenteration and radiotherapy in these cases remains uncertain.
AB - An unsuspected uveal melanoma arising in a phthisical eye extended through the optic nerve to the surgical margin in the orbital apex without involvement of other orbital structures. Step sections showed the continuous extension through the nerve. Factors likely to predispose to optic nerve extension include epithelioid cell type, large tumour size, peripapillary involvement, and glaucoma. Optic nerve extension carries the risks noted with orbital extension of intraocular tumour, but may in addition lead more directly to intracranial invasion, including a chiasmal syndrome. The role of exenteration and radiotherapy in these cases remains uncertain.
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U2 - 10.1136/bjo.68.4.272
DO - 10.1136/bjo.68.4.272
M3 - Article
C2 - 6704363
AN - SCOPUS:0021668109
SN - 0007-1161
VL - 68
SP - 272
EP - 275
JO - British Journal of Ophthalmology
JF - British Journal of Ophthalmology
IS - 4
ER -