Validity, reliability, and responsiveness of SRS-7 as an outcomes assessment instrument for operatively treated patients with adult spinal deformity

Amit Jain, Virginie Lafage, Michael P. Kelly, Hamid Hassanzadeh, Brian J. Neuman, Daniel M. Sciubba, Shay Bess, Christopher I. Shaffrey, Christopher P. Ames, Justin K. Scheer, Douglas Burton, Munish C. Gupta, Robert Hart, Richard A. Hostin, Khaled M. Kebaish

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Study Design. A retrospective analysis. Objective. The aim of our study was to compare the normality, concurrent validity, internal consistency, responsiveness, and dimensionality of an item response theory-derived seven-question instrument (SRS-7), against the Scoliosis Research Society- 22r (SRS-22r) questionnaire in operatively treated patients with adult spinal deformity (ASD). Summary of Background Data. Compared with SRS-22r, SRS-7 (which has been validated in operatively treated patients with adolescent idiopathic scoliosis) has advantages of being short, unidimensional, and linear. Methods. A prospective database of ASD patients was queried for patients 18 years or older who were operatively treated, and who answered pre- and postoperative (at 2-year follow-up) SRS- 22r questions (n=276). Corresponding SRS-7 scores were calculated using answers to SRS-22r items 1, 4, 6, 10, 18, 19, and 20. Significance was set at a P value less than 0.01. Results. SRS-7 and SRS-22r were normally distributed preoperatively but not postoperatively. SRS-7 and SRS-22r scores had high correlation both preoperatively (r=0.76, P<0.01) and postoperatively (r=0.83, P<0.01). The internal consistency reliability Cronbach a values were 0.61 (SRS-7) and 0.83 (SRS- 22r) preoperatively and 0.91 (SRS-7) and 0.95 (SRS-22r) postoperatively. SRS-7 was found to be more responsive than SRS- 22r with measures of effect size: Cohen d=1.21 versus 1.13, Hedge g=1.21 versus 1.13, and effect size correlation r=0.52 versus 0.49. Iterative principal factor analysis of pre- and postoperative scores showed the presence of one dominant latent factor in SRS-7 (unidimensionality) and four latent factors in SRS-22r (multidimensionality). Conclusion. SRS-7 is a valid, reliable, responsive, and unidimensional instrument, which can be used as a short-form alternative to the SRS-22r for assessing global changes in patient-reported outcomes over time in patients with ASD.

Original languageEnglish (US)
Pages (from-to)1463-1468
Number of pages6
JournalSpine
Volume41
Issue number18
DOIs
StatePublished - Sep 15 2016

Keywords

  • Scoliosis Research Society questionnaire
  • adult spinal deformity
  • patient-reported outcomes

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Clinical Neurology

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