Vertebrobasilar Revascularization Rates and Outcomes in the MERCI and Multi-MERCI Trials

Helmi L. Lutsep, Marilyn M. Rymer, Gary M. Nesbit

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


Objective: Mortality of 40% to 86% and good outcomes in only 13% to 21% of patients beg for treatment options for basilar occlusion. This study determined outcomes of patients with vertebrobasilar occlusion treated with mechanical embolus removal in cerebral ischemia (MERCI) retriever mechanical thrombectomy. Methods: Patients with vertebrobasilar occlusion in the MERCI and Multi-MERCI trials received treatment up to 8 hours after symptom onset. Recanalization was determined after retriever use and adjunctive therapy. Mortality and good outcomes, modified Rankin scale score 0-3, were determined at 90 days in patients who were recanalized and not recanalized. Results: Recanalization occurred in 21 of 27 (78%) patients. Mortality was 44% and good outcomes were seen in 41%. Patients with recanalization tended to have better outcomes than those without. Conclusions: Outcomes in patients with vertebrobasilar occlusions treated with the MERCI retriever compared favorably with natural history reports and tended to be better in those patients with recanalization.

Original languageEnglish (US)
Pages (from-to)55-57
Number of pages3
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number2
StatePublished - 2008


  • Mechanical thrombectomy
  • acute stroke
  • basilar artery
  • vertebrobasilar stroke

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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