Visible light sensorless adaptive optics for retinal structure and fluorescence imaging

Myeong Jin Ju; Christine Huang; Daniel J. Wahl; Yifan Jian; Marinko V. Sarunic

doi:10.1364/OL.43.005162

Visible light sensorless adaptive optics for retinal structure and fluorescence imaging

Myeong Jin Ju, Christine Huang, Daniel J. Wahl, Yifan Jian, Marinko V. Sarunic

Ophthalmology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Optical coherence tomography (OCT) has emerged as a powerful imaging instrument and technology in biomedicine. OCT imaging is predominantly performed using wavelengths in the near infrared; however, visible light (VIS) has been recently employed in OCT systems with encouraging results for high-resolution retinal imaging. Using a broadband supercontinuum VIS source, we present a sensorless adaptive optics (SAO) multimodal imaging system driven by VIS-OCT for volumetric retinal structural imaging, followed by the acquisition of fluorescence emission. The coherence-gated, depth-resolved VIS-OCT images used for image-guided SAO aberration correction enable high-resolution structural and fluorescence imaging.

Original language	English (US)
Pages (from-to)	5162-5165
Number of pages	4
Journal	Optics Letters
Volume	43
Issue number	20
DOIs	https://doi.org/10.1364/OL.43.005162
State	Published - Oct 15 2018

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.43.005162

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title = "Visible light sensorless adaptive optics for retinal structure and fluorescence imaging",

abstract = "Optical coherence tomography (OCT) has emerged as a powerful imaging instrument and technology in biomedicine. OCT imaging is predominantly performed using wavelengths in the near infrared; however, visible light (VIS) has been recently employed in OCT systems with encouraging results for high-resolution retinal imaging. Using a broadband supercontinuum VIS source, we present a sensorless adaptive optics (SAO) multimodal imaging system driven by VIS-OCT for volumetric retinal structural imaging, followed by the acquisition of fluorescence emission. The coherence-gated, depth-resolved VIS-OCT images used for image-guided SAO aberration correction enable high-resolution structural and fluorescence imaging.",

author = "Ju, {Myeong Jin} and Christine Huang and Wahl, {Daniel J.} and Yifan Jian and Sarunic, {Marinko V.}",

note = "Publisher Copyright: {\textcopyright} 2018 Optical Society of America.",

year = "2018",

month = oct,

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doi = "10.1364/OL.43.005162",

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AU - Ju, Myeong Jin

AU - Huang, Christine

AU - Wahl, Daniel J.

AU - Jian, Yifan

AU - Sarunic, Marinko V.

PY - 2018/10/15

Y1 - 2018/10/15

N2 - Optical coherence tomography (OCT) has emerged as a powerful imaging instrument and technology in biomedicine. OCT imaging is predominantly performed using wavelengths in the near infrared; however, visible light (VIS) has been recently employed in OCT systems with encouraging results for high-resolution retinal imaging. Using a broadband supercontinuum VIS source, we present a sensorless adaptive optics (SAO) multimodal imaging system driven by VIS-OCT for volumetric retinal structural imaging, followed by the acquisition of fluorescence emission. The coherence-gated, depth-resolved VIS-OCT images used for image-guided SAO aberration correction enable high-resolution structural and fluorescence imaging.

AB - Optical coherence tomography (OCT) has emerged as a powerful imaging instrument and technology in biomedicine. OCT imaging is predominantly performed using wavelengths in the near infrared; however, visible light (VIS) has been recently employed in OCT systems with encouraging results for high-resolution retinal imaging. Using a broadband supercontinuum VIS source, we present a sensorless adaptive optics (SAO) multimodal imaging system driven by VIS-OCT for volumetric retinal structural imaging, followed by the acquisition of fluorescence emission. The coherence-gated, depth-resolved VIS-OCT images used for image-guided SAO aberration correction enable high-resolution structural and fluorescence imaging.

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Visible light sensorless adaptive optics for retinal structure and fluorescence imaging

Abstract

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