Vitiligo and disorders of the retinal pigment epithelium

D. M. Albert, M. D. Wagoner, R. C. Pruett, J. J. Nordlund, A. B. Lerner

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


The association of vitiligo with inflammation of the uveal tract is well established. The relationship between vitiligo and hypopigmentation and/or degeneration of the retinal pigment epithelium (RPE) not secondary to ocular inflammation has not been adequately investigated. Sixty (27%) of 223 consecutive patients with vitiligo were found to have some evidence of RPE phypopigmentation ranging from mild, focal areas of involvement in most cases to extensive RPE degeneration with a retinitis pigmentosa-like syndrome in one patient. Fifteen (25%) patients complained of night blindness. Only 6 (4%) of 148 patients in a control group had similar fundoscopic findings (p<0.001). None of these patients were symptomatic. There have been isolated reports of vitiligo occurring with tapetoretinal degeneration. We report 2 patients with both vitiligo and retinitis pigmentosa.

Original languageEnglish (US)
Pages (from-to)153-156
Number of pages4
JournalUnknown Journal
Issue number3
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


Dive into the research topics of 'Vitiligo and disorders of the retinal pigment epithelium'. Together they form a unique fingerprint.

Cite this