Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly

N. Van Der Velde; W. Meerding; C. Looman; P. Kannus; H. Sievnen; M. Palvanen; A. Darowski; S. Chambers; D. Chambers; P. Thapa; P. Gideon; T. Cost; R. Hubbard; P. Farrington; C. Smith; P. Vestergaard; L. Rejnmark; L. Mosekilde; W. Ray; M. Griffin; E. Malcolm; S. Goldman; K. Stone; S. Ancoli-Israel; R. Asplund; S. Henriksson; S. Johansson; R. Asplund; S. Johansson; S. Henriksson; K. Ensrud; T. Blackwell; S. Ancoli-Israel; J. Teo; N. Briffa; A. Devine; A. Mayers; D. Baldwin; X. Li; R. Hamdy; W. Sandborn; D. Fairweather; J. Kerr; D. Harrison; B. Takkouche; A. Montes-Martnez; S. Gill; E. Haney; B. Chan; S. Diem

doi:10.2165/11204060-000000000-00000

Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly

N. Van Der Velde, W. Meerding, C. Looman, P. Kannus, H. Sievnen, M. Palvanen, A. Darowski, S. Chambers, D. Chambers, P. Thapa, P. Gideon, T. Cost, R. Hubbard, P. Farrington, C. Smith, P. Vestergaard, L. Rejnmark, L. Mosekilde, W. Ray, M. GriffinE. Malcolm, S. Goldman, K. Stone, S. Ancoli-Israel, R. Asplund, S. Henriksson, S. Johansson, R. Asplund, S. Johansson, S. Henriksson, K. Ensrud, T. Blackwell, S. Ancoli-Israel, J. Teo, N. Briffa, A. Devine, A. Mayers, D. Baldwin, X. Li, R. Hamdy, W. Sandborn, D. Fairweather, J. Kerr, D. Harrison, B. Takkouche, A. Montes-Martnez, S. Gill, E. Haney, B. Chan, S. Diem

Department of Medicine

Research output: Contribution to journal › Short survey › peer-review

Abstract

The risk of falls increases in elderly patients receiving treatment with antidepressants. The increased risk is probably attributable to the adverse effects (e.g. sedation, sleep disturbances and subsequent daytime drowsiness, balance problems, orthostatic hypotension and cardiac rhythm disorders) associated with antidepressants.

Original language	English (US)
Pages (from-to)	23-26
Number of pages	4
Journal	Drugs and Therapy Perspectives
Volume	26
Issue number	2
DOIs	https://doi.org/10.2165/11204060-000000000-00000
State	Published - 2010

Keywords

Adrenergic-receptor-antagonists
Adverse reactions
Antidepressants
Elderly
Insomnia
Monoamine-oxidase-inhibitors
Orthostatic-hypotension
Sedation
Serotonin-uptake-inhibitors

ASJC Scopus subject areas

Pharmacology (medical)

Access to Document

10.2165/11204060-000000000-00000

Cite this

Van Der Velde, N., Meerding, W., Looman, C., Kannus, P., Sievnen, H., Palvanen, M., Darowski, A., Chambers, S., Chambers, D., Thapa, P., Gideon, P., Cost, T., Hubbard, R., Farrington, P., Smith, C., Vestergaard, P., Rejnmark, L., Mosekilde, L., Ray, W., ... Diem, S. (2010). Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly. Drugs and Therapy Perspectives, 26(2), 23-26. https://doi.org/10.2165/11204060-000000000-00000

Van Der Velde, N, Meerding, W, Looman, C, Kannus, P, Sievnen, H, Palvanen, M, Darowski, A, Chambers, S, Chambers, D, Thapa, P, Gideon, P, Cost, T, Hubbard, R, Farrington, P, Smith, C, Vestergaard, P, Rejnmark, L, Mosekilde, L, Ray, W, Griffin, M, Malcolm, E, Goldman, S, Stone, K, Ancoli-Israel, S, Asplund, R, Henriksson, S, Johansson, S, Asplund, R, Johansson, S, Henriksson, S, Ensrud, K, Blackwell, T, Ancoli-Israel, S, Teo, J, Briffa, N, Devine, A, Mayers, A, Baldwin, D, Li, X, Hamdy, R, Sandborn, W, Fairweather, D, Kerr, J, Harrison, D, Takkouche, B, Montes-Martnez, A, Gill, S, Haney, E, Chan, B & Diem, S 2010, 'Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly', Drugs and Therapy Perspectives, vol. 26, no. 2, pp. 23-26. https://doi.org/10.2165/11204060-000000000-00000

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abstract = "The risk of falls increases in elderly patients receiving treatment with antidepressants. The increased risk is probably attributable to the adverse effects (e.g. sedation, sleep disturbances and subsequent daytime drowsiness, balance problems, orthostatic hypotension and cardiac rhythm disorders) associated with antidepressants.",

keywords = "Adrenergic-receptor-antagonists, Adverse reactions, Antidepressants, Elderly, Insomnia, Monoamine-oxidase-inhibitors, Orthostatic-hypotension, Sedation, Serotonin-uptake-inhibitors",

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AU - Van Der Velde, N.

AU - Meerding, W.

AU - Looman, C.

AU - Kannus, P.

AU - Sievnen, H.

AU - Palvanen, M.

AU - Darowski, A.

AU - Chambers, S.

AU - Chambers, D.

AU - Thapa, P.

AU - Gideon, P.

AU - Cost, T.

AU - Hubbard, R.

AU - Farrington, P.

AU - Smith, C.

AU - Vestergaard, P.

AU - Rejnmark, L.

AU - Mosekilde, L.

AU - Ray, W.

AU - Griffin, M.

AU - Malcolm, E.

AU - Goldman, S.

AU - Stone, K.

AU - Ancoli-Israel, S.

AU - Asplund, R.

AU - Henriksson, S.

AU - Johansson, S.

AU - Asplund, R.

AU - Johansson, S.

AU - Henriksson, S.

AU - Ensrud, K.

AU - Blackwell, T.

AU - Ancoli-Israel, S.

AU - Teo, J.

AU - Briffa, N.

AU - Devine, A.

AU - Mayers, A.

AU - Baldwin, D.

AU - Li, X.

AU - Hamdy, R.

AU - Sandborn, W.

AU - Fairweather, D.

AU - Kerr, J.

AU - Harrison, D.

AU - Takkouche, B.

AU - Montes-Martnez, A.

AU - Gill, S.

AU - Haney, E.

AU - Chan, B.

AU - Diem, S.

PY - 2010

Y1 - 2010

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KW - Antidepressants

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KW - Insomnia

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KW - Orthostatic-hypotension

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Weigh the benefits of treatment against the increase in the risk of falls when using antidepressant therapy in the elderly

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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