TY - JOUR
T1 - Widefield Optical Coherence Tomography in Pediatric Retina
T2 - A Case Series of Intraoperative Applications Using a Prototype Handheld Device
AU - Nguyen, Thanh Tin P.
AU - Ni, Shuibin
AU - Liang, Guangru
AU - Khan, Shanjida
AU - Wei, Xiang
AU - Skalet, Alison
AU - Ostmo, Susan
AU - Chiang, Michael F.
AU - Jia, Yali
AU - Huang, David
AU - Jian, Yifan
AU - Campbell, J. Peter
N1 - Funding Information:
This work was supported by grants R01 HD107494 and P30 EY10572 from the National Institutes of Health (Bethesda, MD), by unrestricted departmental funding, a Career Development Award (JC) and a Career Advancement Award (YiJ) from Research to Prevent Blindness (New York, NY), and the West Coast Consortium for Technology and Innovations in Pediatrics.
Publisher Copyright:
Copyright © 2022 Nguyen, Ni, Liang, Khan, Wei, Skalet, Ostmo, Chiang, Jia, Huang, Jian and Campbell.
PY - 2022/7/4
Y1 - 2022/7/4
N2 - Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal detachment (exudative, tractional, and rhegmatogenous) may be improved with OCT-based assessment of retinal breaks, identification of proliferative vitreoretinopathy (PVR) membranes, and the pattern of subretinal fluid. Intraocular tumors both benign and malignant often occur outside of the central macula and may be associated with exudation, subretinal and intraretinal fluid, and vitreoretinal traction. The development of wider field OCT systems thus has the potential to improve the diagnosis and management of myriad diseases in both adult and pediatric retina. In this paper, we present a case series of pediatric patients with complex vitreoretinal pathology undergoing examinations under anesthesia (EUA) using a portable widefield (WF) swept-source (SS)-OCT device.
AB - Optical coherence tomography (OCT) has changed the standard of care for diagnosis and management of macular diseases in adults. Current commercially available OCT systems, including handheld OCT for pediatric use, have a relatively narrow field of view (FOV), which has limited the potential application of OCT to retinal diseases with primarily peripheral pathology, including many of the most common pediatric retinal conditions. More broadly, diagnosis of all types of retinal detachment (exudative, tractional, and rhegmatogenous) may be improved with OCT-based assessment of retinal breaks, identification of proliferative vitreoretinopathy (PVR) membranes, and the pattern of subretinal fluid. Intraocular tumors both benign and malignant often occur outside of the central macula and may be associated with exudation, subretinal and intraretinal fluid, and vitreoretinal traction. The development of wider field OCT systems thus has the potential to improve the diagnosis and management of myriad diseases in both adult and pediatric retina. In this paper, we present a case series of pediatric patients with complex vitreoretinal pathology undergoing examinations under anesthesia (EUA) using a portable widefield (WF) swept-source (SS)-OCT device.
KW - handheld optical coherence tomography
KW - optical coherence tomography
KW - optical coherence tomography with angiography
KW - pediatric retina
KW - retina
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U2 - 10.3389/fmed.2022.860371
DO - 10.3389/fmed.2022.860371
M3 - Article
AN - SCOPUS:85134391070
SN - 2296-858X
VL - 9
JO - Frontiers in Medicine
JF - Frontiers in Medicine
M1 - 860371
ER -