X-ray therapy of experimental malignant melanoma of the hamster eye

Robert P. Burns, Clifford V. Allen, Fredrick T. Fraunfelder

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


There has been wide-spread disagreement about the effect of radiation in malignant melanoma. Therefore, the value of orthovoltage X-ray therapy to the eye of hamsters inoculated with five strains of malignant melanoma has been tested in controlled experiments. Tumor size and survival time were measured. X-ray therapy retarded melanoma growth at times. With some cell lines, X-ray therapy appeared to prolong hamster survival; with others, it did not. Neither X-ray therapy nor surgical enucleation of the eye appeared to be clearly superior.

Original languageEnglish (US)
Pages (from-to)328-336
Number of pages9
JournalAmerican journal of ophthalmology
Issue number2
StatePublished - Aug 1969
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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