YAPping about differentiation therapy in muscle cancer

Matthew N. Svalina; Charles Keller

doi:10.1016/j.ccr.2014.07.011

YAPping about differentiation therapy in muscle cancer

Matthew N. Svalina, Charles Keller

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma.

Original language	English (US)
Pages (from-to)	154-155
Number of pages	2
Journal	Cancer Cell
Volume	26
Issue number	2
DOIs	https://doi.org/10.1016/j.ccr.2014.07.011
State	Published - Aug 11 2014
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2014.07.011

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title = "YAPping about differentiation therapy in muscle cancer",

abstract = "Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma.",

author = "Svalina, {Matthew N.} and Charles Keller",

year = "2014",

month = aug,

day = "11",

doi = "10.1016/j.ccr.2014.07.011",

language = "English (US)",

volume = "26",

pages = "154--155",

journal = "Cancer Cell",

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publisher = "Cell Press",

number = "2",

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TY - JOUR

T1 - YAPping about differentiation therapy in muscle cancer

AU - Svalina, Matthew N.

AU - Keller, Charles

PY - 2014/8/11

Y1 - 2014/8/11

N2 - Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma.

AB - Overcoming a presumed differentiation block in the childhood muscle cancer embryonal rhabdomyosarcoma is often thought to hold promise as an approach to replace cytotoxic chemotherapy with molecularly-targeted differentiation therapies. In this issue of Cancer Cell, Tremblay and colleagues implicate YAP1 and the Hippo signaling pathway in the maintenance of differentiation-arrested and proliferative phenotypes for embryonal rhabdomyosarcoma.

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U2 - 10.1016/j.ccr.2014.07.011

DO - 10.1016/j.ccr.2014.07.011

M3 - Short survey

C2 - 25117705

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SN - 1535-6108

VL - 26

SP - 154

EP - 155

JO - Cancer Cell

JF - Cancer Cell

IS - 2

ER -

YAPping about differentiation therapy in muscle cancer

Abstract

ASJC Scopus subject areas

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