Abstract
The tight junction is an intricate seal between adjoining epithelial cells that also separates the apical and basolateral membranes within these cells. A paper in this issue of Cell by Umeda et al. (2006) demonstrates that loss of the ZO scaffolding proteins prevents the formation of tight junctions but surprisingly does not perturb apico-basal polarity.
Original language | English (US) |
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Pages (from-to) | 647-649 |
Number of pages | 3 |
Journal | Cell |
Volume | 126 |
Issue number | 4 |
DOIs | |
State | Published - Aug 25 2006 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)