Vaccine and Gene Therapy Institute

Search results

  • 2023

    Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model

    Otero, C. E., Barfield, R., Scheef, E., Nelson, C. S., Rodgers, N., Wang, H. Y., Moström, M. J., Manuel, T. D., Sass, J., Schmidt, K., Taher, H., Papen, C., Sprehe, L., Kendall, S., Davalos, A., Barry, P. A., Früh, K., Pollara, J., Malouli, D., Chan, C., & 2 othersKaur, A. & Permar, S. R., Oct 2023, In: PLoS pathogens. 19, 10 October, e1011378.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells

    Dubé, M., Tastet, O., Dufour, C., Sannier, G., Brassard, N., Delgado, G. G., Pagliuzza, A., Richard, C., Nayrac, M., Routy, J. P., Prat, A., Estes, J. D., Fromentin, R., Chomont, N. & Kaufmann, D. E., Sep 13 2023, In: Cell Host and Microbe. 31, 9, p. 1507-1522.e5

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Stabilization of the human cytomegalovirus UL136p33 reactivation determinant overcomes the requirement for UL135 for replication in hematopoietic cells

    Moy, M. A., Collins-McMillen, D., Crawford, L., Parkins, C., Zeltzer, S., Caviness, K., Zaidi, S. S. A., Caposio, P. & Goodrum, F., Aug 2023, In: Journal of virology. 97, 8

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

    Harbour, J. C., Abdelbary, M., Schell, J. B., Fancher, S. P., McLean, J. J., Nappi, T. J., Liu, S., Nice, T. J., Xia, Z., Früh, K. & Nolz, J. C., May 30 2023, In: Cell Reports. 42, 5, 112407.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection

    Ricciardi, M. J., Rust, L. N., Nuria, P. L., Yusova, S., Biswas, S., Webb, G. M., Gonzalez-Nieto, L., Voigt, T. B., Louw, J. J., Laurino, F. D., DiBello, J. R., Raué, H. P., Barber-Axthelm, A. M., Chun, K., Uttke, S., Raphael, L. M. S., Yrizarry-Medina, A., Rosen, B. C., Agnor, R., Gao, L., & 13 othersLabriola, C., Axthelm, M., Smedley, J., Julander, J. G., Bonaldo, M. C., Walker, L. M., Messaoudi, I., Slifka, M. K., Burton, D. R., Kallas, E. G., Sacha, J. B., Watkins, D. I. & Burwitz, B. J., Mar 29 2023, In: Science translational medicine. 15, 689, eade5795.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

    Pinkevych, M., Docken, S. S., Okoye, A. A., Fennessey, C. M., Del Prete, G. Q., Pino, M., Harper, J. L., Betts, M. R., Paiardini, M., Keele, B. F. & Davenport, M. P., Oct 2023, In: PLoS pathogens. 19, 10 October, e1011660.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Viral miRNA regulation of host gene expression

    Diggins, N. L. & Hancock, M. H., Sep 15 2023, In: Seminars in Cell and Developmental Biology. 146, p. 2-19 18 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    10 Scopus citations
  • Virology under the Microscope-a Call for Rational Discourse

    Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Jan 2023, In: mBio. 14, 1

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    2 Scopus citations
  • Virology under the Microscope—a Call for Rational Discourse

    Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Feb 2023, In: Journal of virology. 97, 2

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    9 Scopus citations
  • Virology under the Microscope—a Call for Rational Discourse

    Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Apr 2023, In: mSphere. 8, 2

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    2 Scopus citations
  • 2024

    Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

    MacMillen, Z., Hatzakis, K., Simpson, A., Shears, M. J., Watson, F., Erasmus, J. H., Khandhar, A. P., Wilder, B., Murphy, S. C., Reed, S. G., Davie, J. W. & Avril, M., Dec 2024, In: npj Vaccines. 9, 1, 12.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Anti–PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers

    Eichholz, K., Fukazawa, Y., Peterson, C. W., Haeseleer, F., Medina, M., Hoffmeister, S., Duell, D. M., Varco-Merth, B. D., Dross, S., Park, H., Labriola, C. S., Axthelm, M. K., Murnane, R. D., Smedley, J. V., Jin, L., Gong, J., Rust, B. J., Fuller, D. H., Kiem, H. P., Picker, L. J., & 2 othersOkoye, A. A. & Corey, L., Apr 1 2024, In: Journal of Clinical Investigation. 134, 7, e169309.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • CD4dimCD8brightT cells are inversely associated with neuro-inflammatory markers among people with HIV

    Albalawi, Y. A., Shull, T., Virdi, A. K., Subra, C., Mitchell, J., Slike, B. M., Jian, N., Krebs, S. J., Sacdalan, C., Ratnaratorn, N., Hsu, D. C., Phanuphak, N., Spudich, S., Trautmann, L. & Al-Harthi, L., Jan 1 2024, In: AIDS. 38, 1, p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Induction of somatic cell haploidy by premature cell division

    Mikhalchenko, A., Gutierrez, N. M., Frana, D., Safaei, Z., Van Dyken, C., Li, Y., Ma, H., Koski, A., Liang, D., Lee, S. G., Amato, P. & Mitalipov, S., Mar 2024, In: Science Advances. 10, 10, eadk9001.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • SIV Infection Is Associated with Transient Acute-Phase Steatosis in Hepatocytes In Vivo

    Derby, N., Biswas, S., Yusova, S., Luevano-Santos, C., Pacheco, M. C., Meyer, K. A., Johnson, B. I., Fischer, M., Fancher, K. A., Fisher, C., Abraham, Y. M., McMahon, C. J., Lutz, S. S., Smedley, J. V., Burwitz, B. J. & Sodora, D. L., Feb 2024, In: Viruses. 16, 2, 296.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E

    Brackenridge, S., John, N., Früh, K., Borrow, P. & McMichael, A. J., 2024, In: Frontiers in immunology. 15, 1329032.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Virology—the path forward

    Rasmussen, A. L., Gronvall, G. K., Lowen, A. C., Goodrum, F., Alwine, J., Andersen, K. G., Anthony, S. J., Baines, J., Banerjee, A., Broadbent, A. J., Brooke, C. B., Campos, S. K., Caposio, P., Casadevall, A., Chan, G. C., Cliffe, A. R., Collins-McMillen, D., Connell, N., Damania, B., Daugherty, M. D., & 58 othersDebbink, K., Dermody, T. S., DiMaio, D., Duprex, W. P., Emerman, M., Galloway, D. A., Garry, R. F., Goldstein, S. A., Greninger, A. L., Hartman, A. L., Hogue, B. G., Horner, S. M., Hotez, P. J., Jung, J. U., Kamil, J. P., Karst, S. M., Laimins, L., Lakdawala, S. S., Landais, I., Letko, M., Lindenbach, B., Liu, S. L., Luftig, M., McFadden, G., Mehle, A., Morrison, J., Moscona, A., Mühlberger, E., Munger, J., Münger, K., Murphy, E., Neufeldt, C. J., Nikolich, J. Z., O'Connor, C. M., Pekosz, A., Permar, S. R., Pfeiffer, J. K., Popescu, S. V., Purdy, J. G., Racaniello, V. R., Rice, C. M., Runstadler, J. A., Sapp, M. J., Scott, R. S., Smith, G. A., Sorrell, E. M., Speranza, E., Streblow, D., Tibbetts, S. A., Toth, Z., Van Doorslaer, K., Weiss, S. R., White, E. A., White, T. M., Wobus, C. E., Worobey, M., Yamaoka, S. & Yurochko, A., Mar 2024, In: Journal of virology. 98, 3

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • Virology—the path forward

    Rasmussen, A. L., Gronvall, G. K., Lowen, A. C., Goodrum, F., Alwine, J., Andersen, K. G., Anthony, S. J., Baines, J., Banerjee, A., Broadbent, A. J., Brooke, C. B., Campos, S. K., Caposio, P., Casadevall, A., Chan, G. C., Cliffe, A. R., Collins-McMillen, D., Connell, N., Damania, B., Daugherty, M. D., & 58 othersDebbink, K., Dermody, T. S., DiMaio, D., Duprex, W. P., Emerman, M., Galloway, D. A., Garry, R. F., Goldstein, S. A., Greninger, A. L., Hartman, A. L., Hogue, B. G., Horner, S. M., Hotez, P. J., Jung, J. U., Kamil, J. P., Karst, S. M., Laimins, L., Lakdawala, S. S., Landais, I., Letko, M., Lindenbach, B., Liu, S. L., Luftig, M., McFadden, G., Mehle, A., Morrison, J., Moscona, A., Mühlberger, E., Munger, J., Münger, K., Murphy, E., Neufeldt, C. J., Nikolich, J. Z., O'Connor, C. M., Pekosz, A., Permar, S. R., Pfeiffer, J. K., Popescu, S. V., Purdy, J. G., Racaniello, V. R., Rice, C. M., Runstadler, J. A., Sapp, M. J., Scott, R. S., Smith, G. A., Sorrell, E. M., Speranza, E., Streblow, D., Tibbetts, S. A., Toth, Z., Van Doorslaer, K., Weiss, S. R., White, E. A., White, T. M., Wobus, C. E., Worobey, M., Yamaoka, S. & Yurochko, A., Jan 2024, In: Journal of virology. 98, 1

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    5 Scopus citations