Vaccine and Gene Therapy Institute

Research output

Research output per year 1989 2006 2007 2008 2010 2011 2012 2013 2014 2015 2017 2018 2019 2020 2021 2022 2023 2024

• 700 Article
• 82 Review article
• 34 Comment/debate
• 25 Chapter
• 27 More
  • 10 Short survey
  • 8 Letter
  • 7 Editorial
  • 1 Conference contribution
  • 1 Foreword/postscript

Research output per year

Research output per year

Search results

• Viral proteomics: Global evaluation of viruses and their interaction with the host

  Viswanathan, K. & Früh, K., Dec 2007, In: Expert Review of Proteomics. 4, 6, p. 815-829 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Proteomics 100%
  • Proteome 90%
  • Viruses 72%
  • Viral Proteins 46%
  • Protein 44%
  35 Scopus citations

• Viral takeover of the host ubiquitin system

  Gustin, J. K., Moses, A. V., Früh, K. & Douglas, J. L., 2011, In: Frontiers in Microbiology. 2, JULY

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Ubiquitin 100%
  • Viruses 41%
  • DNA Viruses 30%
  • DNA Tumor Viruses 20%
  • Acylation 17%
  51 Scopus citations

• Virogenomics: A novel approach to antiviral drug discovery

  Früh, K., Simmen, K., Luukkonen, B. G. M., Bell, Y. C. & Ghazal, P., Jun 1 2001, In: Drug Discovery Today. 6, 12, p. 621-627 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Antiviral Drug 100%
  • Viral Genome 83%
  • Microarrays 79%
  • Drug Discovery 75%
  • Antiviral Agents 62%
  28 Scopus citations

• Virology—the path forward

  Rasmussen, A. L., Gronvall, G. K., Lowen, A. C., Goodrum, F., Alwine, J., Andersen, K. G., Anthony, S. J., Baines, J., Banerjee, A., Broadbent, A. J., Brooke, C. B., Campos, S. K., Caposio, P., Casadevall, A., Chan, G. C., Cliffe, A. R., Collins-McMillen, D., Connell, N., Damania, B., Daugherty, M. D., & 58 othersDebbink, K., Dermody, T. S., DiMaio, D., Duprex, W. P., Emerman, M., Galloway, D. A., Garry, R. F., Goldstein, S. A., Greninger, A. L., Hartman, A. L., Hogue, B. G., Horner, S. M., Hotez, P. J., Jung, J. U., Kamil, J. P., Karst, S. M., Laimins, L., Lakdawala, S. S., Landais, I., Letko, M., Lindenbach, B., Liu, S. L., Luftig, M., McFadden, G., Mehle, A., Morrison, J., Moscona, A., Mühlberger, E., Munger, J., Münger, K., Murphy, E., Neufeldt, C. J., Nikolich, J. Z., O'Connor, C. M., Pekosz, A., Permar, S. R., Pfeiffer, J. K., Popescu, S. V., Purdy, J. G., Racaniello, V. R., Rice, C. M., Runstadler, J. A., Sapp, M. J., Scott, R. S., Smith, G. A., Sorrell, E. M., Speranza, E., Streblow, D., Tibbetts, S. A., Toth, Z., Van Doorslaer, K., Weiss, S. R., White, E. A., White, T. M., Wobus, C. E., Worobey, M., Yamaoka, S. & Yurochko, A., Mar 2024, In: Journal of virology. 98, 3

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • virology 100%
  • Virology 97%
  • Containment of Biohazards 52%
  • Viruses 50%
  • biosafety 48%

• Virology—the path forward

  Rasmussen, A. L., Gronvall, G. K., Lowen, A. C., Goodrum, F., Alwine, J., Andersen, K. G., Anthony, S. J., Baines, J., Banerjee, A., Broadbent, A. J., Brooke, C. B., Campos, S. K., Caposio, P., Casadevall, A., Chan, G. C., Cliffe, A. R., Collins-McMillen, D., Connell, N., Damania, B., Daugherty, M. D., & 58 othersDebbink, K., Dermody, T. S., DiMaio, D., Duprex, W. P., Emerman, M., Galloway, D. A., Garry, R. F., Goldstein, S. A., Greninger, A. L., Hartman, A. L., Hogue, B. G., Horner, S. M., Hotez, P. J., Jung, J. U., Kamil, J. P., Karst, S. M., Laimins, L., Lakdawala, S. S., Landais, I., Letko, M., Lindenbach, B., Liu, S. L., Luftig, M., McFadden, G., Mehle, A., Morrison, J., Moscona, A., Mühlberger, E., Munger, J., Münger, K., Murphy, E., Neufeldt, C. J., Nikolich, J. Z., O'Connor, C. M., Pekosz, A., Permar, S. R., Pfeiffer, J. K., Popescu, S. V., Purdy, J. G., Racaniello, V. R., Rice, C. M., Runstadler, J. A., Sapp, M. J., Scott, R. S., Smith, G. A., Sorrell, E. M., Speranza, E., Streblow, D., Tibbetts, S. A., Toth, Z., Van Doorslaer, K., Weiss, S. R., White, E. A., White, T. M., Wobus, C. E., Worobey, M., Yamaoka, S. & Yurochko, A., Jan 2024, In: Journal of virology. 98, 1

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • virology 100%
  • Virology 97%
  • Containment of Biohazards 52%
  • Viruses 50%
  • biosafety 48%
  5 Scopus citations

• Virology under the Microscope-a Call for Rational Discourse

  Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Jan 2023, In: mBio. 14, 1

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Virology 100%
  • SARS Virus 45%
  • Viruses 20%
  • Pandemics 16%
  • Administrative Personnel 15%
  2 Scopus citations

• Virology under the Microscope—a Call for Rational Discourse

  Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Feb 2023, In: Journal of virology. 97, 2

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • virology 100%
  • Virology 97%
  • SARS Virus 44%
  • burden of disease 22%
  • Viruses 20%
  9 Scopus citations

• Virology under the Microscope—a Call for Rational Discourse

  Goodrum, F., Lowen, A. C., Lakdawala, S., Alwine, J., Casadevall, A., Imperiale, M. J., Atwood, W., Avgousti, D., Baines, J., Banfield, B., Banks, L., Bhaduri-McIntosh, S., Bhattacharya, D., Blanco-Melo, D., Bloom, D., Boon, A., Boulant, S., Brandt, C., Broadbent, A., Brooke, C., & 136 othersCameron, C., Campos, S., Caposio, P., Chan, G., Cliffe, A., Coffin, J., Collins, K., Damania, B., Daugherty, M., Debbink, K., DeCaprio, J., Dermody, T., Dikeakos, J., DiMaio, D., Dinglasan, R., Duprex, W. P., Dutch, R., Elde, N., Emerman, M., Enquist, L., Fane, B., Fernandez-Sesma, A., Flenniken, M., Frappier, L., Frieman, M., Frueh, K., Gack, M., Gaglia, M., Gallagher, T., Galloway, D., García-Sastre, A., Geballe, A., Glaunsinger, B., Goff, S., Greninger, A., Hancock, M., Harris, E., Heaton, N., Heise, M., Heldwein, E., Hogue, B., Horner, S., Hutchinson, E., Hyser, J., Jackson, W., Kalejta, R., Kamil, J., Karst, S., Kirchhoff, F., Knipe, D., Kowalik, T., Lagunoff, M., Laimins, L., Langlois, R., Lauring, A., Lee, B., Leib, D., Liu, S. L., Longnecker, R., Lopez, C., Luftig, M., Lund, J., Manicassamy, B., McFadden, G., McIntosh, M., Mehle, A., Miller, W. A., Mohr, I., Moody, C., Moorman, N., Moscona, A., Mounce, B., Munger, J., Münger, K., Murphy, E., Naghavi, M., Nelson, J., Neufeldt, C., Nikolich, J., O'Connor, C., Ono, A., Orenstein, W., Ornelles, D., Ou, J. H., Parker, J., Parrish, C., Pekosz, A., Pellett, P., Pfeiffer, J., Plemper, R., Polyak, S., Purdy, J., Pyeon, D., Quinones-Mateu, M., Renne, R., Rice, C., Schoggins, J., Roller, R., Russell, C., Sandri-Goldin, R., Sapp, M., Schang, L., Schmid, S., Schultz-Cherry, S., Semler, B., Shenk, T., Silvestri, G., Simon, V., Smith, G., Smith, J., Spindler, K., Stanifer, M., Subbarao, K., Sundquist, W., Suthar, M., Sutton, T., Tai, A., Tarakanova, V., tenOever, B., Tibbetts, S., Tompkins, S., Toth, Z., van Doorslaer, K., Vignuzzi, M., Wallace, N., Walsh, D., Weekes, M., Weinberg, J., Weitzman, M., Weller, S., Whelan, S., White, E., Williams, B., Wobus, C., Wong, S. & Yurochko, A., Apr 2023, In: mSphere. 8, 2

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Virology 100%
  • SARS Virus 45%
  • Viruses 20%
  • Pandemics 16%
  • Administrative Personnel 15%
  2 Scopus citations

• Visualizing the immune system: Providing key insights into HIV/SIV infections

  Estes, J. D., LeGrand, R. & Petrovas, C., Mar 2 2018, In: Frontiers in immunology. 9, MAR, 423.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • HIV Infections 100%
  • Immune System 89%
  • Technology 29%
  • Adaptive Immunity 23%
  • Stromal Cells 22%
  16 Scopus citations

• Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/tetherin via a βTrCP-dependent mechanism

  Douglas, J. L., Viswanathan, K., McCarroll, M. N., Gustin, J. K., Früh, K. & Moses, A. V., Aug 2009, In: Journal of virology. 83, 16, p. 7931-7947 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bone Marrow Stromal Antigen 2 100%
  • Human immunodeficiency virus 85%
  • Down-Regulation 42%
  • HIV 41%
  • degradation 36%
  289 Scopus citations

• Wake me up before you go: A strategy to reduce the latent HIV reservoir

  Chomont, N., Okoye, A. A., Favre, D. & Trautmann, L., Jan 28 2018, In: AIDS. 32, 3, p. 293-298 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Scopus citations

• West nile virus capsid degradation of claudin proteins disrupts epithelial barrier function

  Medigeshi, G. R., Hirsch, A. J., Brien, J. D., Uhrlaub, J. L., Mason, P. W., Wiley, C., Nikolich-Zugich, J. & Nelson, J. A., Jun 2009, In: Journal of virology. 83, 12, p. 6125-6134 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • West Nile Fever 100%
  • Claudins 97%
  • West Nile virus 88%
  • capsid 81%
  • Capsid 80%
  54 Scopus citations

• West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of αvβ3 integrin

  Medigeshi, G. R., Hirsch, A. J., Streblow, D. N., Nikolich-Zugich, J. & Nelson, J. A., Jun 2008, In: Journal of virology. 82, 11, p. 5212-5219 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Membrane Microdomains 100%
  • West Nile virus 90%
  • integrins 89%
  • Virus Internalization 87%
  • Integrins 67%
  117 Scopus citations

• West Nile virus infection activates the unfolded protein response, leading to CHOP induction and apoptosis

  Medigeshi, G. R., Lancaster, A. M., Hirsch, A. J., Briese, T., Lipkin, W. I., DeFilippis, V., Früh, K., Mason, P. W., Nikolich-Zugich, J. & Nelson, J. A., Oct 2007, In: Journal of virology. 81, 20, p. 10849-10860 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • West Nile Fever 100%
  • unfolded protein response 93%
  • West Nile virus 88%
  • Unfolded Protein Response 86%
  • apoptosis 64%
  190 Scopus citations

• X-chromosome inactivation in monkey embryos and pluripotent stem cells

  Tachibana, M., Ma, H., Sparman, M. L., Lee, H. S., Ramsey, C. M., Woodward, J. S., Sritanaudomchai, H., Masterson, K. R., Wolff, E. E., Jia, Y. & Mitalipov, S. M., Nov 15 2012, In: Developmental Biology. 371, 2, p. 146-155 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • X Chromosome Inactivation 100%
  • Pluripotent Stem Cells 89%
  • Haplorhini 70%
  • Embryonic Structures 62%
  • X-Linked Genes 56%
  18 Scopus citations

• Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques

  Halabi, J., Jagger, B. W., Salazar, V., Winkler, E. S., White, J. P., Humphrey, P. A., Hirsch, A. J., Streblow, D. N., Diamond, M. S. & Moley, K., Apr 7 2020, In: Journal of Infectious Diseases. 221, 9, p. 1506-1517 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus 100%
  • Prostatitis 96%
  • Macaca 84%
  • Prostate 45%
  • Viruses 21%
  16 Scopus citations

• Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology

  Hirsch, A. J., Roberts, V. H. J., Grigsby, P. L., Haese, N., Schabel, M. C., Wang, X., Lo, J. O., Liu, Z., Kroenke, C. D., Smith, J. L., Kelleher, M., Broeckel, R., Kreklywich, C. N., Parkins, C. J., Denton, M., Smith, P., Defilippis, V., Messer, W., Nelson, J. A., Hennebold, J. D., & 12 othersGrafe, M., Colgin, L., Lewis, A., Ducore, R., Swanson, T., Legasse, A. W., Axthelm, M. K., MacAllister, R., Moses, A. V., Morgan, T. K., Frias, A. E. & Streblow, D. N., Dec 1 2018, In: Nature communications. 9, 1, 263.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus Infection 100%
  • infectious diseases 90%
  • viruses 85%
  • Macaca mulatta 75%
  • Fetal Development 44%
  136 Scopus citations

• Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues

  Hirsch, A. J., Smith, J. L., Haese, N. N., Broeckel, R. M., Parkins, C. J., Kreklywich, C., DeFilippis, V. R., Denton, M., Smith, P. P., Messer, W. B., Colgin, L. M. A., Ducore, R. M., Grigsby, P. L., Hennebold, J. D., Swanson, T., Legasse, A. W., Axthelm, M. K., MacAllister, R., Wiley, C. A., Nelson, J. A., & 1 othersStreblow, D. N., Mar 2017, In: PLoS pathogens. 13, 3, e1006219.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika virus 100%
  • Zika Virus Infection 90%
  • Zika Virus 85%
  • Macaca mulatta 67%
  • Conjunctivitis 52%
  180 Scopus citations