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X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
Krishnamurthy, H. & Gouaux, E., Jan 26 2012, In: Nature. 481, 7382, p. 469-474 6 p.Research output: Contribution to journal › Article › peer-review
Open Access419 Scopus citations -
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
Althoff, T., Hibbs, R. E., Banerjee, S. & Gouaux, E., Aug 21 2014, In: Nature. 512, 7514, p. 333-337 5 p.Research output: Contribution to journal › Article › peer-review
Open Access201 Scopus citations -
X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine
Penmatsa, A., Wang, K. H. & Gouaux, E., Jun 3 2015, In: Nature Structural and Molecular Biology. 22, 6, p. 506-508 3 p.Research output: Contribution to journal › Article › peer-review
Open Access126 Scopus citations -
X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Chen, L., Dürr, K. L. & Gouaux, E., Aug 29 2014, In: Science (New York, N.Y.). 345, 6200, p. 1021-1026 6 p.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
X-ray structures define human P2X 3 receptor gating cycle and antagonist action
Mansoor, S. E., Lü, W., Oosterheert, W., Shekhar, M., Tajkhorshid, E. & Gouaux, E., Sep 14 2016, In: Nature. 538, 7623, p. 66-71 6 p.Research output: Contribution to journal › Article › peer-review
Open Access178 Scopus citations -
X-ray structures and mechanism of the human serotonin transporter
Coleman, J. A., Green, E. M. & Gouaux, E., Apr 21 2016, In: Nature. 532, 7599, p. 334-339 6 p.Research output: Contribution to journal › Article › peer-review
Open Access469 Scopus citations -
X-ray structure of the mammalian GIRK2-βγ G-protein complex
Whorton, M. R. & MacKinnon, R., 2013, In: Nature. 498, 7453, p. 190-197 8 p.Research output: Contribution to journal › Article › peer-review
Open Access253 Scopus citations -
X-ray structure of dopamine transporter elucidates antidepressant mechanism
Penmatsa, A., Wang, K. H. & Gouaux, E., 2013, In: Nature. 503, 7474, p. 85-90 6 p.Research output: Contribution to journal › Article › peer-review
Open Access487 Scopus citations -
X-ray structure of acid-sensing ion channel 1-snake toxin complex reveals open state of a Na+-selective channel
Baconguis, I., Bohlen, C. J., Goehring, A., Julius, D. & Gouaux, E., Feb 13 2014, In: Cell. 156, 4, p. 717-729 13 p.Research output: Contribution to journal › Article › peer-review
Open Access232 Scopus citations -
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
Sobolevsky, A. I., Rosconi, M. P. & Gouaux, E., Dec 10 2009, In: Nature. 462, 7274, p. 745-756 12 p.Research output: Contribution to journal › Article › peer-review
Open Access856 Scopus citations -
X-ray powder diffraction data and thermal expansion of N(CH3)4Br and N(CH3)4I
Xenopoulos, A., Ralle, M., Habenschuss, A. & Wunderlich, B., Sep 1996, In: Powder Diffraction. 11, 3, p. 246-249 4 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
X-ray laser microscopy of rat sperm nuclei
Da Silva, L. B., Trebes, J. E., Balhorn, R., Mrowka, S., Anderson, E., Attwood, D. T., Barbee, T. W., Brase, J., Corzett, M., Gray, J., Koch, J. A., Lee, C., Kern, D., London, R. A., MacGowan, B. J., Matthews, D. L. & Stone, G., 1992, In: Science. 258, 5080, p. 269-271 3 p.Research output: Contribution to journal › Article › peer-review
137 Scopus citations -
X-ray laser holography of biological microstructures
Trebes, J., Brase, J., Gray, J., London, R., Matthews, D., Peters, D., Pinkel, D., Stone, G., Rosen, M. & Yorkey, T., 1990, Institute of Physics Conference Series. 116 ed. Publ by Inst of Physics Publ Ltd, p. 279-287 9 p. (Institute of Physics Conference Series; no. 116).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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X-ray holography for sequencing DNA
Yorkey, T., Brase, J., Trebes, J., Lane, S. & Gray, J., 1990, In: Proceedings of SPIE - The International Society for Optical Engineering. 1345, p. 255-259 5 p.Research output: Contribution to journal › Conference article › peer-review
3 Scopus citations -
X-ray holography for sequencing DNA
Yorkey, T., Brase, J., Trebes, J., Lane, S. & Gray, J., Dec 27 1990, In: Proceedings of SPIE - The International Society for Optical Engineering. 1347, p. 474-478 5 p.Research output: Contribution to journal › Conference article › peer-review
2 Scopus citations -
X-ray crystallographic and functional studies of thyroid hormone receptor
Ribeiro, R. C. J., Apriletti, J. W., Wagner, R. L., Feng, W., Kushner, P. J., Nilsson, S., Scanlan, T. S., West, B. L., Fletterick, R. J. & Baxter, J. D., 1998, In: Journal of Steroid Biochemistry and Molecular Biology. 65, 1-6, p. 133-141 9 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
X-ray absorption studies on the mixed-valence and fully reduced forms of the soluble Cu(A) domains of cytochrome c oxidase
Blackburn, N. J., De Vries, S., Barr, M. E., Houser, R. P., Tolman, W. B., Sanders, D. & Fee, J. A., 1997, In: Journal of the American Chemical Society. 119, 26, p. 6135-6143 9 p.Research output: Contribution to journal › Article › peer-review
93 Scopus citations -
X-ray Absorption Studies of Three-Coordinate Dicopper(I) Complexes and Their Dioxygen Adducts
Blackburn, N. J., Strange, R. W., Farooq, A., Haka, M. S. & Karlin, K. D., Jun 1988, In: Journal of the American Chemical Society. 110, 13, p. 4263-4272 10 p.Research output: Contribution to journal › Article › peer-review
82 Scopus citations -
X-ray Absorption Studies of the Cu-Dependent Phenylalanine Hydroxylase from Chromobacterium violaceum. Comparison of the Copper Coordination in Oxidized and Dithionite-Reduced Enzymes
Blackburn, N. J., Strange, R. W., Carr, R. T. & Benkovic, S. J., Feb 1 1992, In: Biochemistry. 31, 23, p. 5298-5303 6 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu(I) center capable of adduct formation with exogenous thiols and phosphines
Ralle, M., Lutsenko, S. & Blackburn, N. J., Jun 20 2003, In: Journal of Biological Chemistry. 278, 25, p. 23163-23170 8 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
X-ray Absorption Spectroscopy of Metal-Histidine Coordination in Metalloproteins. Exact Simulation of the EXAFS of Tetrakis(imidazole)copper(II) Nitrate and Other Copper-Imidazole Complexes by the Use of a Multiple-Scattering Treatment
Strange, R. W., Blackburn, N. J., Knowles, P. F. & Hasnain, S. S., Nov 1 1987, In: Journal of the American Chemical Society. 109, 23, p. 7157-7162 6 p.Research output: Contribution to journal › Article › peer-review
126 Scopus citations -
X-ray Absorption Edge Spectroscopy of Copper(I) Complexes. Coordination Geometry of Copper(I) in the Reduced Forms of Copper Proteins and Their Derivatives with Carbon Monoxide
Blackburn, N. J., Strange, R. W., Reedijk, J., Volbeda, A., Farooq, A., Zubieta, J. & Karlin, K. D., Apr 1 1989, In: Inorganic Chemistry. 28, 7, p. 1349-1357 9 p.Research output: Contribution to journal › Article › peer-review
79 Scopus citations -
XPKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells
Israelsen, W. J., Dayton, T. L., Davidson, S. M., Fiske, B. P., Hosios, A. M., Bellinger, G., Li, J., Yu, Y., Sasaki, M., Horner, J. W., Burga, L. N., Xie, J., Jurczak, M. J., Depinho, R. A., Clish, C. B., Jacks, T., Kibbey, R. G., Wulf, G. M., Di Vizio, D., Mills, G. B., & 2 others , Oct 10 2013, In: Cell. 155, 2, p. 397 1 p.Research output: Contribution to journal › Article › peer-review
Open Access398 Scopus citations -
X-linked retinitis pigmentosa associated with a 2-base pair insertion in codon 99 of the RP3 gene RPGR
Weleber, R. G., Butler, N. S., Murphey, W. H., Sheffield, V. C. & Stone, E. M., 1997, In: Archives of ophthalmology. 115, 11, p. 1429-1435 7 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
X-Linked Recessive Cone Dystrophy With Tapetal-Like Sheen: A Newly Recognized Entity With Mizuo-Nakamura Phenomenon
Heckenlively, J. R. & Weleber, R. G., Sep 1986, In: Archives of ophthalmology. 104, 9, p. 1322-1328 7 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
X-linked peripheral retinoschisis without macular involvement: a case series with RS1 genetic confirmation
Smith, L. M., Cernichiaro-Espinosa, L. A., McKeown, C. A., Tekin, M., Lam, B. L., Chiang, J., Russell, J. F. & Berrocal, A. M., Jan 2 2020, In: Ophthalmic Genetics. 41, 1, p. 57-62 6 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
X-linked inheritance of Fanconi anemia complementation group B
Meetei, A. R., Levitus, M., Xue, Y., Medhurst, A. L., Zwaan, M., Ling, C., Rooimans, M. A., Bier, P., Hoatlin, M., Pals, G., De Winter, J. P., Wang, W. & Joenje, H., Nov 2004, In: Nature genetics. 36, 11, p. 1219-1224 6 p.Research output: Contribution to journal › Article › peer-review
Open Access254 Scopus citations -
X-linked hypohidrotic ectodermal dysplasia: localization within the region Xq11-21.1 by linkage analysis and implications for carrier detection and prenatal diagnosis
Zonana, J., Clarke, A., Sarfarazi, M., Thomas, N. S. T., Roberts, K., Marymee, K. & Harper, P. S., 1988, In: American Journal of Human Genetics. 43, 1, p. 75-85 11 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein
Kere, J., Srivastava, A. K., Montonen, O., Zonana, J., Thomas, N., Ferguson, B., Munoz, F., Morgan, D., Clarke, A., Baybayan, P., Chen, E. Y., Ezer, S., Saarialho-Kere, U., De La Chapelle, A. & Schlessinger, D., Aug 1996, In: Nature genetics. 13, 4, p. 409-416 8 p.Research output: Contribution to journal › Article › peer-review
618 Scopus citations -
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XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
Asselin, E., Mills, G. B. & Tsang, B. K., Mar 1 2001, In: Cancer Research. 61, 5, p. 1862-1868 7 p.Research output: Contribution to journal › Article › peer-review
322 Scopus citations -
XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction
Thomaston, J. L., Woldeyes, R. A., Nakane, T., Yamashita, A., Tanaka, T., Koiwai, K., Brewster, A. S., Barad, B. A., Chen, Y., Lemmin, T., Uervirojnangkoorn, M., Arima, T., Kobayashi, J., Masuda, T., Suzuki, M., Sugahara, M., Sauter, N. K., Tanaka, R., Nureki, O., Tono, K., & 6 others , Dec 19 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 51, p. 13357-13362 6 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
Xenopus δ-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases
Gu, D., Sater, A. K., Ji, H., Cho, K., Clark, M., Stratton, S. A., Barton, M. C., Lu, Q. & McCrea, P. D., Nov 15 2009, In: Journal of Cell Science. 122, 22, p. 4049-4061 13 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells
Shin, J. B., Adams, D., Paukert, M., Siba, M., Sidi, S., Levin, M., Gillespie, P. G. & Gründer, S., Aug 30 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 35, p. 12572-12577 6 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Xenopus laevis contains two nonallelic preproinsulin genes. cDNA cloning and evolutionary perspective
Shuldiner, A. R., Phillips, S., Roberts, C. T., LeRoith, D. & Roth, J., 1989, In: Journal of Biological Chemistry. 264, 16, p. 9428-9432 5 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
Xenon arc panretinal photocoagulation for central retinal vein occlusion: A randomized prospective study
May, D. R., Klein, M. L., Peyman, G. A. & Raichand, M., 1979, In: British Journal of Ophthalmology. 63, 11, p. 725-734 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Xenon anesthesia for all, or only a select few?
Neice, A. E. & Zornow, M. H., Nov 1 2016, In: Anaesthesia. 71, 11, p. 1267-1272 6 p.Research output: Contribution to journal › Editorial › peer-review
Open Access25 Scopus citations -
Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
Moss, M. I., Pauli, M., Moreau, J. M., Cohen, J. N., Rosenblum, M. D. & Lowe, M. M., Jun 2022, In: Journal of Visualized Experiments. 2022, 184, e64040.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors
Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N., Barczak, A., Xiao, Y., Korkaya, H., Baehner, F., Lewicki, J., Wicha, M., Park, J. W., Spellman, P. T., Gray, J. W., Van'T Veer, L. & Esserman, L. J., Oct 2012, In: Breast Cancer Research and Treatment. 135, 3, p. 913-922 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk
Goode, E. L., White, K. L., Vierkant, R. A., Phelan, C. M., Cunningham, J. M., Schildkraut, J. M., Berchuck, A., Larson, M. C., Fridley, B. L., Olson, J. E., Webb, P. M., Chen, X., Beesley, J., Chenevix-Trench, G. & Sellers, T. A., May 2011, In: Molecular Carcinogenesis. 50, 5, p. 397-402 6 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
XeCl laser-induced fluorescence of atherosclerotic arteries: Spectral similarities between lipid-rich lesions and peroxidized lipoproteine
Oraevsky, A. A., Jacques, S. L., Pettit, G. H., Sauerbrey, R. A., Tittel, F. K., Nguy, J. H. & Henry, P. D., Jan 1993, In: Circulation research. 72, 1, p. 84-90 7 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
XeCl laser ablation of atherosclerotic aorta: Luminescence spectroscopy of ablation products
Oraevsky, A. A., Jacques, S. L., Pettit, G. H., Tittel, F. K. & Henry, P. D., 1993, In: Lasers in Surgery and Medicine. 13, 2, p. 168-178 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
XeCl laser ablation of atherosclerotic aorta: Optical properties and energy pathways
Oraevsky, A. A., Jacques, S. L., Pettit, G. H., Saidi, I. S., Tittel, F. K. & Henry, P. D., 1992, In: Lasers in Surgery and Medicine. 12, 6, p. 585-597 13 p.Research output: Contribution to journal › Article › peer-review
66 Scopus citations -
XeCI laser-induced fluorescence detection of peroxidized lipoproteins in lipid-rich atherosclerotic lesions
Oraevsky, A. A., Henry, P. D., Jacques, S. L. & Titte, F. K., Jun 23 1993, In: Proceedings of SPIE - The International Society for Optical Engineering. 1878, p. 31-41 11 p.Research output: Contribution to journal › Conference article › peer-review
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X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila
Legube, G., McWeeney, S. K., Lercher, M. J. & Akhtar, A., Apr 1 2006, In: Genes and Development. 20, 7, p. 871-883 13 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
X chromosome-inactivation patterns in 31 individuals with PHACE syndrome
Sullivan, C. T., Christian, S. L., Shieh, J. T. C., Metry, D., Blei, F., Krol, A., Drolet, B. A., Frieden, I. J., Dobyns, W. B. & Siegel, D. H., Mar 2013, In: Molecular Syndromology. 4, 3, p. 114-118 5 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
X-chromosome inactivation in monkey embryos and pluripotent stem cells
Tachibana, M., Ma, H., Sparman, M. L., Lee, H. S., Ramsey, C. M., Woodward, J. S., Sritanaudomchai, H., Masterson, K. R., Wolff, E. E., Jia, Y. & Mitalipov, S. M., Nov 15 2012, In: Developmental Biology. 371, 2, p. 146-155 10 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome
Liu, K., Kurien, B. T., Zimmerman, S. L., Kaufman, K. M., Taft, D. H., Kottyan, L. C., Lazaro, S., Weaver, C. A., Ice, J. A., Adler, A. J., Chodosh, J., Radfar, L., Rasmussen, A., Stone, D. U., Lewis, D. M., Li, S., Koelsch, K. A., Igoe, A., Talsania, M., Kumar, J., & 58 others , May 1 2016, In: Arthritis and Rheumatology. 68, 5, p. 1290-1300 11 p.Research output: Contribution to journal › Article › peer-review
Open Access109 Scopus citations -
XAS Studies on the CuA Centers of Heme-Copper Oxidases and Loop-Directed Mutants of Azurin: Implications for Redox Reactivity
Blackburn, N. J., Ralle, M., Sanders, D., Fee, J. A., De Vries, S., Houser, R. P., Tolman, W. B., Hay, M. T. & Lu, Y., 1998, In: ACS Symposium Series. 692, p. 241-259 19 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
XAS structural comparisons of reversibly interconvertible oxo- and hydroxo-bridged heme-copper oxidase model compounds
Fox, S., Nanthakumar, A., Wikström, M., Karlin, K. D. & Blackburn, N. J., Jan 10 1996, In: Journal of the American Chemical Society. 118, 1, p. 24-34 11 p.Research output: Contribution to journal › Review article › peer-review
79 Scopus citations