A child with eosinophilia, Loeffler endocarditis, and acute lymphoblastic leukemia

Matthew D. Files; Joseph A. Zenel; Laurie B. Armsby; Stephen M. Langley

doi:10.1007/s00246-008-9360-7

A child with eosinophilia, Loeffler endocarditis, and acute lymphoblastic leukemia

Matthew D. Files, Joseph A. Zenel, Laurie B. Armsby, Stephen M. Langley

Pediatrics

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We present an 8-year-old male with Loeffler endocarditis and acute lymphoblastic leukemia with hypereosinophilia (ALL/Eo) who initially presented with a 3-month history of peripheral eosinophilia thought to be due to visceral larval migrans. Despite treatment for Toxocara, his leukocytosis persisted and he developed mitral valve insufficiency and congestive heart failure. Myocardial biopsy revealed fibrosis and thrombus formation indicative of Loeffler endocarditis, and a peripheral smear showed pre-B-cell acute lymphoid leukemia. This unique case highlights a rare, yet serious sequella of prolonged eosinophilia.

Original language	English (US)
Pages (from-to)	530-532
Number of pages	3
Journal	Pediatric Cardiology
Volume	30
Issue number	4
DOIs	https://doi.org/10.1007/s00246-008-9360-7
State	Published - May 1 2009

Keywords

Congestive heart failure
Eosinophilia
Loeffler endocarditis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Cardiology and Cardiovascular Medicine

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10.1007/s00246-008-9360-7

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abstract = "We present an 8-year-old male with Loeffler endocarditis and acute lymphoblastic leukemia with hypereosinophilia (ALL/Eo) who initially presented with a 3-month history of peripheral eosinophilia thought to be due to visceral larval migrans. Despite treatment for Toxocara, his leukocytosis persisted and he developed mitral valve insufficiency and congestive heart failure. Myocardial biopsy revealed fibrosis and thrombus formation indicative of Loeffler endocarditis, and a peripheral smear showed pre-B-cell acute lymphoid leukemia. This unique case highlights a rare, yet serious sequella of prolonged eosinophilia.",

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AU - Files, Matthew D.

AU - Zenel, Joseph A.

AU - Armsby, Laurie B.

AU - Langley, Stephen M.

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N2 - We present an 8-year-old male with Loeffler endocarditis and acute lymphoblastic leukemia with hypereosinophilia (ALL/Eo) who initially presented with a 3-month history of peripheral eosinophilia thought to be due to visceral larval migrans. Despite treatment for Toxocara, his leukocytosis persisted and he developed mitral valve insufficiency and congestive heart failure. Myocardial biopsy revealed fibrosis and thrombus formation indicative of Loeffler endocarditis, and a peripheral smear showed pre-B-cell acute lymphoid leukemia. This unique case highlights a rare, yet serious sequella of prolonged eosinophilia.

AB - We present an 8-year-old male with Loeffler endocarditis and acute lymphoblastic leukemia with hypereosinophilia (ALL/Eo) who initially presented with a 3-month history of peripheral eosinophilia thought to be due to visceral larval migrans. Despite treatment for Toxocara, his leukocytosis persisted and he developed mitral valve insufficiency and congestive heart failure. Myocardial biopsy revealed fibrosis and thrombus formation indicative of Loeffler endocarditis, and a peripheral smear showed pre-B-cell acute lymphoid leukemia. This unique case highlights a rare, yet serious sequella of prolonged eosinophilia.

KW - Congestive heart failure

KW - Eosinophilia

KW - Loeffler endocarditis

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A child with eosinophilia, Loeffler endocarditis, and acute lymphoblastic leukemia

Abstract

Keywords

ASJC Scopus subject areas

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