TY - JOUR
T1 - A clinicopathologic correlative study of noncontact transscleral Nd:YAG cyclophotocoagulation
AU - Marsh, P.
AU - Wilson, D. J.
AU - Samples, J. R.
AU - Morrison, J. C.
N1 - Funding Information:
Accepted for publication Jan. 28, 1993. From the Casey Eye Institute, Oregon Health Sciences University, Portland, Oregon. This study was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, New York. Reprint requests to David J. Wilson, M.D., Casey Eye Institute, 3375 S.W. TerwiIliger, Portland, OR 97201.
PY - 1993
Y1 - 1993
N2 - We studied the histopathologic changes of three eyes enucleated two weeks, eight weeks, and 17 months, respectively, after noncontact Nd:YAG cyclophotocoagulation. The histologic findings at two weeks were destruction of the nonpigmented and pigmented ciliary body epithelium, occlusion of the capillaries of the ciliary processes, and ciliary body stromal necrosis in the region of the processes. Hyperplasia of the pigmented and nonpigmented epithelium, fibrosis and near total atrophy of the ciliary processes, and partial atrophy of the ciliary muscles were present at eight weeks and 17 months. We concluded that application of treatment 1.0 to 1.5 mm posterior to the corneoscleral limbus selectively destroys the pars plicata, and that, histologically, the mechanism for reducing intraocular pressure appears to be destruction of ciliary processes with reduction of aqueous formation.
AB - We studied the histopathologic changes of three eyes enucleated two weeks, eight weeks, and 17 months, respectively, after noncontact Nd:YAG cyclophotocoagulation. The histologic findings at two weeks were destruction of the nonpigmented and pigmented ciliary body epithelium, occlusion of the capillaries of the ciliary processes, and ciliary body stromal necrosis in the region of the processes. Hyperplasia of the pigmented and nonpigmented epithelium, fibrosis and near total atrophy of the ciliary processes, and partial atrophy of the ciliary muscles were present at eight weeks and 17 months. We concluded that application of treatment 1.0 to 1.5 mm posterior to the corneoscleral limbus selectively destroys the pars plicata, and that, histologically, the mechanism for reducing intraocular pressure appears to be destruction of ciliary processes with reduction of aqueous formation.
UR - http://www.scopus.com/inward/record.url?scp=0027158022&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027158022&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(14)71456-4
DO - 10.1016/S0002-9394(14)71456-4
M3 - Article
C2 - 8488911
AN - SCOPUS:0027158022
SN - 0002-9394
VL - 115
SP - 597
EP - 602
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 5
ER -