A Critical Assessment of Research on Neurotransmitters in Alzheimer's Disease

P. Hemachandra Reddy

    Research output: Contribution to journalReview articlepeer-review

    33 Scopus citations

    Abstract

    The purpose of this mini-forum, "Neurotransmitters and Alzheimer's Disease", is to critically assess the current status of neurotransmitters in Alzheimer's disease. Neurotransmitters are essential neurochemicals that maintain synaptic and cognitive functions in mammals, including humans, by sending signals across pre- to post-synaptic neurons. Authorities in the fields of synapses and neurotransmitters of Alzheimer's disease summarize the current status of basic biology of synapses and neurotransmitters, and also update the current status of clinical trials of neurotransmitters in Alzheimer's disease. This article discusses the prevalence, economic impact, and stages of Alzheimer's dementia in humans.

    Original languageEnglish (US)
    Pages (from-to)969-974
    Number of pages6
    JournalJournal of Alzheimer's Disease
    Volume57
    Issue number4
    DOIs
    StatePublished - 2017

    Keywords

    • Amyloid-β
    • cognitive decline
    • mitochondrial dysfunction
    • synaptic pathology

    ASJC Scopus subject areas

    • General Neuroscience
    • Clinical Psychology
    • Geriatrics and Gerontology
    • Psychiatry and Mental health

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