A Normal Initial Colonoscopy After Age 50 Does Not Predict a Polyp‐free Status for Life

Steven Squillace, Paul Berggreen, Phil Jaffe, M. Brian Fennerty, Lee Hixson, Harinder Garewal, Richard E. Sampliner

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Objectives: The prevalence of colon polyps increases with age in the general population. It is unknown whether a lack of adenomatous polyps determined at one time point after the age of 50 is predictive of a subsequent low risk of polyp development. Methods: Twenty‐nine patients between ages 50 and 70 who had no prior history of polyps and had a normal colonoscopy at least 5 yr previously were recruited for follow‐up colonoscopy to evaluate the incidence of neoplastic disease in this presumably low‐risk group. Results: The incidence of adenomatous polyps after a mean of 5.74 yr was 41.4% (95% confidence interval: 23.5–61.1%). A total of 20 adenomatous polyps were found in 12 patients. Seven polyps were 5 mm or more in size. Conclusions: We conclude that in patients with no history of colonic neoplasia who are 50 yr old, or older, the finding of a normal colonoscopy does not predict diminished risk of neoplasia.

Original languageEnglish (US)
Pages (from-to)1156-1159
Number of pages4
JournalThe American journal of gastroenterology
Issue number8
StatePublished - Aug 1994
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


Dive into the research topics of 'A Normal Initial Colonoscopy After Age 50 Does Not Predict a Polyp‐free Status for Life'. Together they form a unique fingerprint.

Cite this