Abstract
Background: Nijmegen Breakage Syndrome (NBS) is a rare autosomal recessive DNA repair disorder that increases risk of hematological malignancy. Primary gastric malignancies are exceedingly rare in pediatric patients and not typically high on the differential of abdominal pain. Case presentation: A 14-year-old male with NBS presented with persistent abdominal pain and was diagnosed with primary Hodgkin disease of the stomach. Conclusions: In pediatric patients with predisposition to malignancies, such as those with underlying chromosome instability disorders, all symptoms must be carefully considered.
Original language | English (US) |
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Article number | 189 |
Journal | BMC Pediatrics |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Dec 2023 |
Keywords
- Case Report
- Childhood cancer
- Hodgkin disease
- Malnutrition
- Nijmegen Breakage Syndrome
- Primary gastric lymphoma
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health