TY - JOUR
T1 - A real-time 3-dimensional digital Doppler method for measurement of flow rate and volume through mitral valve in children
T2 - A validation study compared with magnetic resonance imaging
AU - Ge, Shuping
AU - Bu, Liping
AU - Zhang, Honghai
AU - Schelbert, Erik
AU - Disterhoft, Michelle
AU - Li, Xiangning
AU - Li, Xiaokui
AU - Sahn, David
AU - Stolpen, Alan
AU - Sonka, Milan
N1 - Funding Information:
This project was funded in part by a Collaborative Interdisciplinary Project Grant Award from University of Iowa.
PY - 2005/1
Y1 - 2005/1
N2 - We developed and assessed a real-time 3-dimensional (3D) digital Doppler method for measurement of flow volumes through the mitral valve in children. A total of 13 children (aged 10.46 ± 2.5 years; 8 boys/5 girls) were enrolled. An ultrasound system (Sonos 7500, Philips, Andover, Mass) was used to acquire raw 3D velocity data for flow measurement based on Gaussian control surface theorem [flow (mL/s) = mean velocity × flow area]. Stroke volume (SV) measured by real-time 3D digital Doppler with the control surface at the mitral valve annulus or orifice was compared with the SV by phase velocity cine magnetic resonance imaging (MRI) at the ascending aorta and by left ventricular volumetric MRI measurement. The best correlation and agreement were seen at the mitral valve orifice by real-time 3D digital Doppler compared with SV by phase velocity cine MRI at the ascending aorta (r = 0.92, mean difference = -5.2 ± 12.0 mL) and SV by left ventricular volumetric MRI measurement (r = 0.94, mean difference = -0.2 ± 10.3 mL).
AB - We developed and assessed a real-time 3-dimensional (3D) digital Doppler method for measurement of flow volumes through the mitral valve in children. A total of 13 children (aged 10.46 ± 2.5 years; 8 boys/5 girls) were enrolled. An ultrasound system (Sonos 7500, Philips, Andover, Mass) was used to acquire raw 3D velocity data for flow measurement based on Gaussian control surface theorem [flow (mL/s) = mean velocity × flow area]. Stroke volume (SV) measured by real-time 3D digital Doppler with the control surface at the mitral valve annulus or orifice was compared with the SV by phase velocity cine magnetic resonance imaging (MRI) at the ascending aorta and by left ventricular volumetric MRI measurement. The best correlation and agreement were seen at the mitral valve orifice by real-time 3D digital Doppler compared with SV by phase velocity cine MRI at the ascending aorta (r = 0.92, mean difference = -5.2 ± 12.0 mL) and SV by left ventricular volumetric MRI measurement (r = 0.94, mean difference = -0.2 ± 10.3 mL).
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U2 - 10.1016/j.echo.2004.08.021
DO - 10.1016/j.echo.2004.08.021
M3 - Article
C2 - 15637481
AN - SCOPUS:19944391883
SN - 0894-7317
VL - 18
SP - 1
EP - 7
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 1
ER -