TY - GEN
T1 - A scalable robotic-based laboratory automation system for medium-sized biotechnology laboratories
AU - Najmabadi, Peyman
AU - Goldenberg, Andrew A.
AU - Emili, Andrew
PY - 2005
Y1 - 2005
N2 - This paper presents a new approach to laboratory automation integration with applications in automatic execution of various biotechnology (Genomics and Proteomics) protocols. The new configuration is called "Tower-based configuration". It provides a scalable workcell that also includes instrumentation for sub-processes such as vortexing, shaking, incubation etc. Tower-based automation is a robotic-based configuration that allows improving the throughput of automated system without changing the robotic workspace or increasing the footprint of the system. Tower configuration consists of two arms mounted on a common cylindrical base, and is surrounded by stackers that carry laboratory processing instruments, labwares and other accessories. The requirement of high throughput is satisfied by parallel processing. A conceptual Tower-based automated system for magnetic isolation of TAP tagged protein complexes protocol is presented and compared with a traditional automated system. Our performance investigation showed that the Tower-based configuration has a high throughput to footprint ratio, high scalability, and wide protocol flexibility in comparison with traditional laboratory automation approaches.
AB - This paper presents a new approach to laboratory automation integration with applications in automatic execution of various biotechnology (Genomics and Proteomics) protocols. The new configuration is called "Tower-based configuration". It provides a scalable workcell that also includes instrumentation for sub-processes such as vortexing, shaking, incubation etc. Tower-based automation is a robotic-based configuration that allows improving the throughput of automated system without changing the robotic workspace or increasing the footprint of the system. Tower configuration consists of two arms mounted on a common cylindrical base, and is surrounded by stackers that carry laboratory processing instruments, labwares and other accessories. The requirement of high throughput is satisfied by parallel processing. A conceptual Tower-based automated system for magnetic isolation of TAP tagged protein complexes protocol is presented and compared with a traditional automated system. Our performance investigation showed that the Tower-based configuration has a high throughput to footprint ratio, high scalability, and wide protocol flexibility in comparison with traditional laboratory automation approaches.
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U2 - 10.1109/COASE.2005.1506763
DO - 10.1109/COASE.2005.1506763
M3 - Conference contribution
AN - SCOPUS:33745940346
SN - 0780394267
SN - 9780780394261
T3 - Proceedings of the 2005 IEEE Conference on Automation Science and Engineering, IEEE-CASE 2005
SP - 166
EP - 171
BT - Proceedings of the 2005 IEEE Conference on Automation Science and Engineering, IEEE-CASE 2005
T2 - 2005 IEEE Conference on Automation Science and Engineering, IEEE-CASE 2005
Y2 - 1 August 2005 through 2 August 2005
ER -