Abstract
This study describes a simplified approach for the interpretation of etectrocardiographic and thallium-201 imaging data derived from the same patient during exercise. The 383 patients in this study had also undergone selective coronary adenography within 3 months of the exercise test. This matrix approach allows for multiple test outcomes (both tests positive, both negative, 1 test positive and 1 negative) and multiple disease states (no coronary artery disease vs 1-vessel vs multivessel coronary artery disease). Because this approach analyzes the results of 2 test outcomes simultaneously rather than serially, it also negates the lack of test independence, if such an effect is present. It is also demonstrated that ST-segment depression on the electrocardiogram and defects on initial thallium-201 images provide conditionally independent information regarding the presence of coronary artery disease in patients without prior myocardial infarction. In contrast, ST-segment depression on the electrocardiogram and redistribution on the delayed thallium-201 images may not provide totally independent information regarding the presence of exercise-induced ischemia in patients with or without myocardial infarction.
Original language | English (US) |
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Pages (from-to) | 466-470 |
Number of pages | 5 |
Journal | The American journal of cardiology |
Volume | 64 |
Issue number | 8 |
DOIs | |
State | Published - Sep 1 1989 |
Externally published | Yes |
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine