Acute generalized exanthematous pustulosis: Atypical presentations and outcomes

T. C. Kostopoulos, S. M. Krishna, N. K. Brinster, A. G. Ortega-Loayza

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


Acute generalized exanthematous pustulosis (AGEP) is an acute drug eruption characterized by erythematous plaques and papules studded with numerous, pinpoint pustules. Several atypical clinical presentations and triggers of AGEP have been described in the literature. These include systemic presentations similar to toxic epidermal necrolysis (TEN) and drug-induced hypersensitivity syndrome (DIHS) and localized presentations mimicking other medication reactions. We herein aim to review atypical presentations and medication triggers of AGEP to assist clinicians in recognizing this condition and making appropriate therapeutic interventions.

Original languageEnglish (US)
Pages (from-to)209-214
Number of pages6
JournalJournal of the European Academy of Dermatology and Venereology
Issue number2
StatePublished - Feb 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases


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