TY - JOUR
T1 - Acute macular neuroretinopathy
T2 - A comprehensive review of the literature
AU - Bhavsar, Kavita V.
AU - Lin, Sally
AU - Rahimy, Ehsan
AU - Joseph, Anthony
AU - Freund, K. Bailey
AU - Sarraf, David
AU - Cunningham, Emmett T.
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Acute macular neuroretinopathy is a relatively rare condition originally defined by the presence of intraretinal, reddish-brown, wedge-shaped lesions, the apices of which tend to point toward the fovea. Acute onset of paracentral scotomas corresponding to the clinically evident lesions is both common and characteristic. Although the pathogenesis of acute macular neuroretinopathy is complex, recent research suggests a microvascular etiology. Advances in multimodal imaging have enabled better characterization of this retinal disorder and have led to newly proposed diagnostic criteria. We review 101 reported cases in the English and non-English language literature identified from 1975, when acute macular neuroretinopathy was first described, to December, 2014. We discuss common risk factors, demographic and clinical characteristics, and multimodal imaging findings, which together provide insights into pathogenesis and guide areas of future investigation.
AB - Acute macular neuroretinopathy is a relatively rare condition originally defined by the presence of intraretinal, reddish-brown, wedge-shaped lesions, the apices of which tend to point toward the fovea. Acute onset of paracentral scotomas corresponding to the clinically evident lesions is both common and characteristic. Although the pathogenesis of acute macular neuroretinopathy is complex, recent research suggests a microvascular etiology. Advances in multimodal imaging have enabled better characterization of this retinal disorder and have led to newly proposed diagnostic criteria. We review 101 reported cases in the English and non-English language literature identified from 1975, when acute macular neuroretinopathy was first described, to December, 2014. We discuss common risk factors, demographic and clinical characteristics, and multimodal imaging findings, which together provide insights into pathogenesis and guide areas of future investigation.
KW - AMN
KW - AMNR
KW - AMOR
KW - DCI
KW - PAMM
KW - acute macular neuroretinopathy
KW - deep capillary ischemia
KW - multimodal imaging
KW - optical coherence tomography
KW - paracentral acute middle maculopathy
UR - http://www.scopus.com/inward/record.url?scp=84964220571&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84964220571&partnerID=8YFLogxK
U2 - 10.1016/j.survophthal.2016.03.003
DO - 10.1016/j.survophthal.2016.03.003
M3 - Review article
C2 - 26973287
AN - SCOPUS:84964220571
SN - 0039-6257
VL - 61
SP - 538
EP - 565
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
IS - 5
ER -