TY - JOUR
T1 - Addressing hereditary cancer risk at the end of life
AU - Roeland, Eric J.
AU - Dullea, Alexandra D.
AU - Hagmann, Chelsea H.
AU - Madlensky, Lisa
N1 - Publisher Copyright:
Copyright © 2017 by American Society of Clinical Oncology.
PY - 2017/10
Y1 - 2017/10
N2 - Oncology guidelines clearly outline evidence-based recommendations for patients with newly diagnosed cancer to help oncologists determine which patients are appropriate for a genetic assessment. Ideally, patients with newly diagnosed cancer, who have personal or family histories suggestive of hereditary cancer predisposition, are referred for genetics work up in the nonurgent setting. However, in some cases, a genetics work up is delayed until the end of life. This is a time of heightened stress and additional obstacles, including discordance between family members regarding the obtainment of genetic information, paying for testing, selecting a surrogate to receive and disperse information in the case of a patient's death, and the use of DNA banking for future evaluation. To meaningfully participate and support patients, family members, and our colleagues facing requests at the end of life for genetic testing, we provide a practical approach and highlight resources to effectively engage in this rising challenge.
AB - Oncology guidelines clearly outline evidence-based recommendations for patients with newly diagnosed cancer to help oncologists determine which patients are appropriate for a genetic assessment. Ideally, patients with newly diagnosed cancer, who have personal or family histories suggestive of hereditary cancer predisposition, are referred for genetics work up in the nonurgent setting. However, in some cases, a genetics work up is delayed until the end of life. This is a time of heightened stress and additional obstacles, including discordance between family members regarding the obtainment of genetic information, paying for testing, selecting a surrogate to receive and disperse information in the case of a patient's death, and the use of DNA banking for future evaluation. To meaningfully participate and support patients, family members, and our colleagues facing requests at the end of life for genetic testing, we provide a practical approach and highlight resources to effectively engage in this rising challenge.
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U2 - 10.1200/JOP.2017.021980
DO - 10.1200/JOP.2017.021980
M3 - Article
C2 - 28541788
AN - SCOPUS:85032501561
SN - 1554-7477
VL - 13
SP - e851-e856
JO - Journal of oncology practice
JF - Journal of oncology practice
IS - 10
ER -