Abstract
Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95% adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95% confidence interval (CI) 1.32-6.50) and low monthly income <50 US$ [OR = 2.77, 95% CI 1.64-4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.
Original language | English (US) |
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Pages (from-to) | 38-41 |
Number of pages | 4 |
Journal | International Journal of STD and AIDS |
Volume | 16 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2005 |
Externally published | Yes |
Keywords
- Adherence
- Antiretroviral therapy
- Self-purchasing
- Sub-Saharan Africa
ASJC Scopus subject areas
- Dermatology
- Public Health, Environmental and Occupational Health
- Infectious Diseases
- Pharmacology (medical)