Advances in prevention and treatment of cerebral palsy

Mario C. Petersen, Frederick B. Palmer

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


In recent years there have been a number of advances in understanding of predisposing and protective factors in the development of cerebral palsy in infants. Multiple gestation births, maternal infection, and maternal and fetal thrombophilic conditions all predispose to the development of CP in the infant. Opportunities for prevention of CP may develop from an improved understanding of these factors and their mechanisms of operation. Similar progress has been made in the evaluation of treatments for CP and the effects of these treatments on the individual's impairment, function, and disability. Selective posterior rhizotomy and Botulinum toxin A are now widely used in the treatment of spasticity. The challenge remains to determine how effectively these promising interventions can alter long-term function and quality of life outcomes in children and adults with CP.

Original languageEnglish (US)
Pages (from-to)30-37
Number of pages8
JournalMental Retardation and Developmental Disabilities Research Reviews
Issue number1
StatePublished - 2001


  • CP
  • Cerebral palsy
  • Risk
  • Thrombophilia
  • Treatment of spasticity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Genetics(clinical)


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