Altered affinity of insulin-like growth factor II (IGF-II) for receptors and IGF-binding proteins, resulting from limited modifications of the IGF-II molecule

Keyphrases

• Insulin-like Growth Factor Binding Protein (IGFBP) 100%
• Receptor-interacting Protein Kinase 1 (RIPK1) 100%
• IGF2 100%
• Insulin-like Growth Factor 2 100%
• Binding Affinity 30%
• Acetylation 30%
• Cysteine Bridge 30%
• Insulin-like Growth Factor 1 Receptor (IGF1R) 20%
• Severe Impairment 20%
• Insulin Receptor 20%
• Type-II Receptor 20%
• Three Dimensional Structure 20%
• N-terminus 10%
• Amino Acids 10%
• Insulin-like Growth factor-1 10%
• Binding Protein 10%
• Recombinant Human 10%
• Amino Acid Variation 10%
• Human Serum 10%
• Binding Data 10%
• C-terminal Amino Acids 10%
• Minor Effect 10%
• N-terminal Amino Acids 10%
• Analog Synthesis 10%
• General Care 10%
• Charge Changes 10%

Biochemistry, Genetics and Molecular Biology

• Binding Protein 100%
• Insulin-Like Growth Factor 2 100%
• Amino Acids 44%
• Binding Affinity 33%
• Acetylation 33%
• Cysteine 33%
• N-Terminus 22%
• Synapsin I 22%
• Insulin-Like Growth Factor 1 Receptor 22%
• Insulin Receptor 22%
• C-Terminus 11%
• Insulin-Like Growth Factor 2 Receptor 11%
• Serum (Blood) 11%