Angiotensin-converting enzyme and cardiovascular disease risk

Jean Pruss O'Malley; Cheryl L. Maslen; D. Roger Illingworth

doi:10.1097/00041433-199910000-00005

Angiotensin-converting enzyme and cardiovascular disease risk

Jean Pruss O'Malley, Cheryl L. Maslen, D. Roger Illingworth

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

The published studies of the association of the angiotensin-converting enzyme (ACE) genotype with cardiovascular disease have used many different diagnostic criteria for cardiovascular disease and have drawn their samples from different patient groups and different populations. This review examines the association of the ACE DD genotype with cardiovascular disease risk in studies grouped by their case criterion, the geographical region of the population samples, and by the cardiovascular risk level of the patient sample. In studies where the underlying odds ratios are determined to be homogeneous, the overall odds ratios for myocardial infarction and coronary artery disease with regard to the ACE DD genotype are estimated using the Mantel-Haenszel method.

Original language	English (US)
Pages (from-to)	407-415
Number of pages	9
Journal	Current opinion in lipidology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1097/00041433-199910000-00005
State	Published - 1999

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Molecular Biology
Genetics
Nutrition and Dietetics
Cardiology and Cardiovascular Medicine
Cell Biology

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10.1097/00041433-199910000-00005

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Angiotensin-converting enzyme and cardiovascular disease risk

Abstract

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