TY - JOUR
T1 - Anterior Uveitis following COVID Vaccination
T2 - A Summary of Cases from Global Reporting Systems
AU - Nanji, Afshan A.
AU - Fraunfelder, Frederick T.
N1 - Funding Information:
Supported by Grant P30 EY010572 from the National Institutes of Health (Bethesda, MD) and by unrestricted departmental funding from Research to Prevent Blindness (New York, NY). The Uppsala Monitoring Center has provided some of the data, but the study results and conclusions are those of the authors and not necessarily those of the Uppsala Monitoring Centre, National Centres, or World Health Organization.
Publisher Copyright:
© 2022 Taylor & Francis Group, LLC.
PY - 2022
Y1 - 2022
N2 - Purpose: COVID-19 vaccines are currently undergoing long-term safety monitoring, including for ocular side effects. Uveitis following vaccination has been described previously with other vaccines and warrants evaluation for COVID-19 vaccines, especially given their widespread use. Case Reports: We present two cases of patients who developed anterior uveitis following the Moderna COVID-19 vaccine, as reported to the National Registry for Drug-Induced Ocular Side Effects. We also summarize reports of anterior uveitis following COVID-19 vaccination as reported to the World Health Organization global database of individual case safety reports. Conclusions: Based on the temporal pattern of ocular inflammation following vaccine delivery in these cases, an association may be present between uveitis and COVID-19 vaccination. Further investigation to explore this association is warranted to guide patient care.
AB - Purpose: COVID-19 vaccines are currently undergoing long-term safety monitoring, including for ocular side effects. Uveitis following vaccination has been described previously with other vaccines and warrants evaluation for COVID-19 vaccines, especially given their widespread use. Case Reports: We present two cases of patients who developed anterior uveitis following the Moderna COVID-19 vaccine, as reported to the National Registry for Drug-Induced Ocular Side Effects. We also summarize reports of anterior uveitis following COVID-19 vaccination as reported to the World Health Organization global database of individual case safety reports. Conclusions: Based on the temporal pattern of ocular inflammation following vaccine delivery in these cases, an association may be present between uveitis and COVID-19 vaccination. Further investigation to explore this association is warranted to guide patient care.
KW - COVID-19
KW - National Registry of Drug-Induced Ocular Side Effects
KW - Uppsala Monitoring Center
KW - anterior uveitis
KW - vaccine
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U2 - 10.1080/09273948.2022.2042316
DO - 10.1080/09273948.2022.2042316
M3 - Letter
C2 - 35226563
AN - SCOPUS:85125889338
SN - 0927-3948
VL - 30
SP - 1244
EP - 1246
JO - Ocular Immunology and Inflammation
JF - Ocular Immunology and Inflammation
IS - 5
ER -