Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids

Sunny Manohar; Antonella Pepe; Christian E. Vélez Gerena; Beatriz Zayas; Sanjay V. Malhotra; Diwan S. Rawat

doi:10.1039/c3ra45333b

Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids

Sunny Manohar, Antonella Pepe, Christian E. Vélez Gerena, Beatriz Zayas, Sanjay V. Malhotra, Diwan S. Rawat

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

In this study the potential for anticancer activity of 4-aminoquinoline- triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.

Original language	English (US)
Pages (from-to)	7062-7067
Number of pages	6
Journal	RSC Advances
Volume	4
Issue number	14
DOIs	https://doi.org/10.1039/c3ra45333b
State	Published - 2014
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

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10.1039/c3ra45333b

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title = "Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids",

abstract = "In this study the potential for anticancer activity of 4-aminoquinoline- triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.",

author = "Sunny Manohar and Antonella Pepe and {V{\'e}lez Gerena}, {Christian E.} and Beatriz Zayas and Malhotra, {Sanjay V.} and Rawat, {Diwan S.}",

year = "2014",

doi = "10.1039/c3ra45333b",

language = "English (US)",

volume = "4",

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journal = "RSC Advances",

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T1 - Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids

AU - Manohar, Sunny

AU - Pepe, Antonella

AU - Vélez Gerena, Christian E.

AU - Zayas, Beatriz

AU - Malhotra, Sanjay V.

AU - Rawat, Diwan S.

PY - 2014

Y1 - 2014

N2 - In this study the potential for anticancer activity of 4-aminoquinoline- triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.

AB - In this study the potential for anticancer activity of 4-aminoquinoline- triazine based hybrids has been investigated on 60 human cancer cell lines (NCI 60). The representative compounds show activity on a range of cell lines and apoptosis as the mode of growth inhibition.

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U2 - 10.1039/c3ra45333b

DO - 10.1039/c3ra45333b

M3 - Article

AN - SCOPUS:84892653165

SN - 2046-2069

VL - 4

SP - 7062

EP - 7067

JO - RSC Advances

JF - RSC Advances

IS - 14

ER -

Anticancer activity of 4-aminoquinoline-triazine based molecular hybrids

Abstract

ASJC Scopus subject areas

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