TY - JOUR
T1 - Association of Race with Survival in Intracranial World Health Organization Grade II and III Meningioma in the United States
T2 - Systematic Literature Review
AU - Elder, Theresa
AU - Ejikeme, Tiffany
AU - Felton, Peter
AU - Raghavan, Alankrita
AU - Wright, James
AU - Wright, Christina Huang
AU - Zhou, Xiaofei
AU - Duncan, Kelsey
AU - Sajatovic, Martha
AU - Hodges, Tiffany
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2020/6
Y1 - 2020/6
N2 - Background: Recent literature has shown significant differences in meningioma incidence among different races, but minimal conclusive data exist on the role of race and ethnicity in overall survival for patients with high-grade intracranial meningioma. We conducted a systematic review to investigate the impact of race and ethnicity on survival in patients with high-grade intracranial meningioma. Methods: A systematic literature review was conducted for studies using Ovid, PubMed, Cochrane, Embase, and Scopus databases. Databases were queried for the following: Meningioma AND [Ethnic OR Demography, OR African American OR Arab OR Hispanic OR Asian, OR White OR race OR racial] AND [survival OR survival analysis OR survival rate OR treatment outcome OR Survivor OR Outcome]. Results: A literature search yielded a total of 412 abstracts, which were screened according to criteria that were determined a priori, and a total of 129 full-text articles were reviewed. Four articles were included in the final analysis, reporting on a total of 13,424 patients. Three studies saw an overall survival benefit in White non-Hispanics compared with Black non-Hispanics, and 1 reported a survival benefit in White non-Hispanics and Black non-Hispanics among patients who received gross total resection. One study additionally reported an increased likelihood of White patients receiving gross total resection when compared with non-White patients. Conclusions: The limited data available suggest that White patients have improved measures of survival compared with nonw-White patients, for reasons that are likely complex and multifactorial. Further studies are needed to explore these survival differences seen.
AB - Background: Recent literature has shown significant differences in meningioma incidence among different races, but minimal conclusive data exist on the role of race and ethnicity in overall survival for patients with high-grade intracranial meningioma. We conducted a systematic review to investigate the impact of race and ethnicity on survival in patients with high-grade intracranial meningioma. Methods: A systematic literature review was conducted for studies using Ovid, PubMed, Cochrane, Embase, and Scopus databases. Databases were queried for the following: Meningioma AND [Ethnic OR Demography, OR African American OR Arab OR Hispanic OR Asian, OR White OR race OR racial] AND [survival OR survival analysis OR survival rate OR treatment outcome OR Survivor OR Outcome]. Results: A literature search yielded a total of 412 abstracts, which were screened according to criteria that were determined a priori, and a total of 129 full-text articles were reviewed. Four articles were included in the final analysis, reporting on a total of 13,424 patients. Three studies saw an overall survival benefit in White non-Hispanics compared with Black non-Hispanics, and 1 reported a survival benefit in White non-Hispanics and Black non-Hispanics among patients who received gross total resection. One study additionally reported an increased likelihood of White patients receiving gross total resection when compared with non-White patients. Conclusions: The limited data available suggest that White patients have improved measures of survival compared with nonw-White patients, for reasons that are likely complex and multifactorial. Further studies are needed to explore these survival differences seen.
KW - Atypical meningioma
KW - High-grade meningioma
KW - Malignant meningioma
KW - Race
KW - Survival
UR - http://www.scopus.com/inward/record.url?scp=85082459167&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85082459167&partnerID=8YFLogxK
U2 - 10.1016/j.wneu.2020.02.120
DO - 10.1016/j.wneu.2020.02.120
M3 - Article
C2 - 32142947
AN - SCOPUS:85082459167
SN - 1878-8750
VL - 138
SP - e361-e369
JO - World Neurosurgery
JF - World Neurosurgery
ER -