Association of Transport Time, Proximity, and Emergency Department Pediatric Readiness with Pediatric Survival at US Trauma Centers

Nina E. Glass, Apoorva Salvi, Ran Wei, Amber Lin, Susan Malveau, Jennifer N.B. Cook, N. Clay Mann, Randall S. Burd, Peter C. Jenkins, Matthew Hansen, Nicholas M. Mohr, Caroline Stephens, Mary E. Fallat, E. Brooke Lerner, Brendan G. Carr, Stephen P. Wall, Craig D. Newgard

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Importance: Emergency department (ED) pediatric readiness is associated with improved survival among children. However, the association between geographic access to high-readiness EDs in US trauma centers and mortality is unclear. Objective: To evaluate the association between the proximity of injury location to receiving trauma centers, including the level of ED pediatric readiness, and mortality among injured children. Design, Setting, and Participants: This retrospective cohort study used a standardized risk-adjustment model to evaluate the association between trauma center proximity, ED pediatric readiness, and in-hospital survival. There were 765 trauma centers (level I-V, adult and pediatric) that contributed data to the National Trauma Data Bank (January 1, 2012, through December 31, 2017) and completed the 2013 National Pediatric Readiness Assessment (conducted from January 1 through August 31, 2013). The study comprised children aged younger than 18 years who were transported by ground to the included trauma centers. Data analysis was performed between January 1 and March 31, 2022. Exposures: Trauma center proximity within 30 minutes by ground transport and ED pediatric readiness, as measured by weighted pediatric readiness score (wPRS; range, 0-100; quartiles 1 [low readiness] to 4 [high readiness]). Main Outcomes and Measures: In-hospital mortality. We used a patient-level mixed-effects logistic regression model to evaluate the association of transport time, proximity, and ED pediatric readiness on mortality. Results: This study included 212689 injured children seen at 765 trauma centers. The median patient age was 10 (IQR, 4-15) years, 136538 (64.2%) were male, and 127885 (60.1%) were White. A total of 4156 children (2.0%) died during their hospital stay. The median wPRS at these hospitals was 79.1 (IQR, 62.9-92.7). A total of 105871 children (49.8%) were transported to trauma centers with high-readiness EDs (wPRS quartile 4) and another 36330 children (33.7%) were injured within 30 minutes of a quartile 4 ED. After adjustment for confounders, proximity, and transport time, high ED pediatric readiness was associated with lower mortality (highest-readiness vs lowest-readiness EDs by wPRS quartiles: adjusted odds ratio, 0.65 [95% CI, 0.47-0.89]). The survival benefit of high-readiness EDs persisted for transport times up to 45 minutes. The findings suggest that matching children to trauma centers with high-readiness EDs within 30 minutes of the injury location may have potentially saved 468 lives (95% CI, 460-476 lives), but increasing all trauma centers to high ED pediatric readiness may have potentially saved 1655 lives (95% CI, 1647-1664 lives). Conclusions and Relevance: These findings suggest that trauma centers with high ED pediatric readiness had lower mortality after considering transport time and proximity. Improving ED pediatric readiness among all trauma centers, rather than selective transport to trauma centers with high ED readiness, had the largest association with pediatric survival. Thus, increased pediatric readiness at all US trauma centers may substantially improve patient outcomes after trauma..

Original languageEnglish (US)
Pages (from-to)1078-1087
Number of pages10
JournalJAMA Surgery
Volume158
Issue number10
DOIs
StatePublished - Oct 11 2023

ASJC Scopus subject areas

  • Surgery

Fingerprint

Dive into the research topics of 'Association of Transport Time, Proximity, and Emergency Department Pediatric Readiness with Pediatric Survival at US Trauma Centers'. Together they form a unique fingerprint.

Cite this