@article{5aa1f04dbd6b4729977b4fce56038ba4,
title = "Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial",
abstract = "A polygenic risk score (PGS) is associated with obstructive coronary artery disease (CAD) independent of traditional risk factors. Coronary computed tomography angiography (CTA) can characterize coronary plaques, including features of highrisk CAD. However, it is unknown if a PGS is associated with obstructive CAD and high-risk CAD phenotypes in patients with symptoms suggestive of CAD.",
author = "Newman, {Jonathan D.} and Douglas, {Pamela S.} and Ilya Zhbannikov and Maros Ferencik and Borek Foldyna and Udo Hoffmann and Shah, {Svati H.} and Ginsburg, {Geoffrey S.} and Lu, {Michael T.} and Deepak Voora",
note = "Funding Information: Dr. Lu has received grant support from has received grant support from AstraZeneca/MedImmune and Kowa, and consulting fees from PQBypass outside the submitted work. Funding Information: Dr. Shah has received grants from the American Heart Association, National Institutes of Health, Baseline Study LLC, AstraZeneca Inc, and Lilly Inc; and has served on the American Heart Association National Board outside of the submitted work. Funding Information: Dr. Voora has received grant support from American Heart Association, National Institutes of Health, AztraZeneca, and Abbott Diagnostics that are outside the submitted work. He is a consultant for Sanford Imagenetics, Optum Labs, and Optum Genomics. Funding Information: Dr. Foldyna reports unrelated grant support from NIH/NHLBI, MedImmune/Astrazeneca, and MedTrace. Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",
year = "2022",
month = oct,
doi = "10.1016/j.ahj.2022.05.012",
language = "English (US)",
volume = "252",
pages = "12--15",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
}