Atopic dermatitis

Eric L. Simpson, Jon M. Hanifin

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations


A topic dermatitis (AD) is an eczematous, highly pruritic chronic inflammatory skin disease. It usually begins early in life and often occurs in people with a personal or family history of asthma and allergic rhinitis. The prevalence is high, especially in children, and it has been rising in recent decades, in parallel with asthma prevalence. Although AD is often described as an "allergic" disease, allergic causation is difficult to document, and AD is increasingly viewed as a skin disease that predisposes to allergies. This interpretation, based on clinical, epidemiologic, and animal studies, may greatly influence our approach to therapy and prevention of atopic diseases in the coming years.

Original languageEnglish (US)
Pages (from-to)149-167
Number of pages19
JournalMedical Clinics of North America
Issue number1
StatePublished - Jan 2006
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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