TY - JOUR
T1 - Audiometric hearing status of individuals with and without multiple sclerosis
AU - Samantha Lewis, M.
AU - Lilly, David J.
AU - Hutter, Michele M.
AU - Bourdette, Dennis N.
AU - McMillan, Garnett P.
AU - Fitzpatrick, Mary A.
AU - Fausti, Stephen A.
PY - 2010
Y1 - 2010
N2 - The purpose of the present investigation was to determine whether differences exist in audiometric hearing status between individuals with and without multiple sclerosis (MS) and between individuals with relapsing-remitting MS (RRMS) and individuals with secondary progressive MS (SPMS). Forty-seven subjects with MS (26 with RRMS and 21 with SPMS) and forty-nine control subjects without MS completed both a comprehensive case-history questionnaire and a conventional hearing evaluation. Statistical analyses, accounting for the potential confounding factors of age, sex, noise exposure, and use of ototoxic medications, revealed significant differences in hearing thresholds between subjects with and without MS at select audiometric test frequencies (p < 0.05). At these audiometric test frequencies, the subjects with MS had poorer hearing thresholds. Additional analyses revealed significant differences in hearing sensitivity at select audiometric frequencies between the subjects with RRMS and the subjects with SPMS, such that those with SPMS had poorer hearing thresholds. These findings have significant clinical implications for practitioners working with patients with MS.
AB - The purpose of the present investigation was to determine whether differences exist in audiometric hearing status between individuals with and without multiple sclerosis (MS) and between individuals with relapsing-remitting MS (RRMS) and individuals with secondary progressive MS (SPMS). Forty-seven subjects with MS (26 with RRMS and 21 with SPMS) and forty-nine control subjects without MS completed both a comprehensive case-history questionnaire and a conventional hearing evaluation. Statistical analyses, accounting for the potential confounding factors of age, sex, noise exposure, and use of ototoxic medications, revealed significant differences in hearing thresholds between subjects with and without MS at select audiometric test frequencies (p < 0.05). At these audiometric test frequencies, the subjects with MS had poorer hearing thresholds. Additional analyses revealed significant differences in hearing sensitivity at select audiometric frequencies between the subjects with RRMS and the subjects with SPMS, such that those with SPMS had poorer hearing thresholds. These findings have significant clinical implications for practitioners working with patients with MS.
KW - Audiometric hearing status
KW - Auditory function
KW - Hearing
KW - Hearing loss
KW - Multiple sclerosis
KW - Pure tone thresholds
KW - Relapsing-remitting multiple sclerosis
KW - Secondary progressive multiple sclerosis
KW - Speech reception threshold
KW - Word recognition
UR - http://www.scopus.com/inward/record.url?scp=78149478038&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78149478038&partnerID=8YFLogxK
U2 - 10.1682/JRRD.2010.01.0010
DO - 10.1682/JRRD.2010.01.0010
M3 - Article
C2 - 21110263
AN - SCOPUS:78149478038
SN - 0748-7711
VL - 47
SP - 669
EP - 678
JO - Journal of Rehabilitation Research and Development
JF - Journal of Rehabilitation Research and Development
IS - 7
ER -