TY - JOUR
T1 - Automatic microelectrode recording analysis and visualization of the globus pallidus interna and stereotactic trajectory
AU - Falkenberg, Jon Haakon
AU - McNames, James
AU - Burchiel, Kim J.
PY - 2006/6
Y1 - 2006/6
N2 - Locating deep brain neuronal structures is required to accurately place deep brain stimulation (DBS) electrodes during stereotactic surgery in patients with Parkinson's disease and other movement disorders. This study investigates the efficacy of automatic microelectrode visualization and analysis methods to help neurosurgeons locate target structures more objectively, consistently, and easily during surgery. Ten patients (4 males and 6 females) who underwent bilateral implantation of DBS electrodes in the globus pallidus interna (Gpi), from 2001 to 2003, at the Oregon Health and Science University and the Portland Veterans Administration Medical Center were included. We compared the efficacy of the microelectrode recording signal energy, power spectral density (PSD), marginal probability density (mPDF), autocorrelation function (ACF), and partial ACF. mPDF and PSD estimates most accurately indicated the borders of the GPi target structure.
AB - Locating deep brain neuronal structures is required to accurately place deep brain stimulation (DBS) electrodes during stereotactic surgery in patients with Parkinson's disease and other movement disorders. This study investigates the efficacy of automatic microelectrode visualization and analysis methods to help neurosurgeons locate target structures more objectively, consistently, and easily during surgery. Ten patients (4 males and 6 females) who underwent bilateral implantation of DBS electrodes in the globus pallidus interna (Gpi), from 2001 to 2003, at the Oregon Health and Science University and the Portland Veterans Administration Medical Center were included. We compared the efficacy of the microelectrode recording signal energy, power spectral density (PSD), marginal probability density (mPDF), autocorrelation function (ACF), and partial ACF. mPDF and PSD estimates most accurately indicated the borders of the GPi target structure.
KW - Deep brain stimulation
KW - Globus pallidus interna
KW - Microelectrode recording analysis
KW - Parkinson's disease
KW - Stereotactic surgery
UR - http://www.scopus.com/inward/record.url?scp=33745447991&partnerID=8YFLogxK
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U2 - 10.1159/000093720
DO - 10.1159/000093720
M3 - Article
C2 - 16741375
AN - SCOPUS:33745447991
SN - 1011-6125
VL - 84
SP - 28
EP - 34
JO - Stereotactic and Functional Neurosurgery
JF - Stereotactic and Functional Neurosurgery
IS - 1
ER -