Bacteriocin-Related Siblicide in Clinical Isolates of Enterococci

Yun Chan Hwang, Susan E. Flannagan, Don B. Clewell, Christine M. Sedgley

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Siblicide is a phenomenon defined in the present context as an Enterococcus strain that, while growing as a colony on solid media, exhibits an inhibitory effect on a lawn composed of the identical strain. It was shown to occur in seven clinical isolates of enterococci (one E. faecalis and six E. faecium). Four involve inhibitory anti-listerial activities consistent with class II bacteriocins, two of which appear to be up-regulated by extracellular autoinducers.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalProbiotics and Antimicrobial Proteins
Issue number1
StatePublished - Mar 2011
Externally publishedYes


  • Bacteriocin
  • Enterococcus faecalis
  • Enterococcus faecium
  • Siblicide
  • Vancomycin-resistance

ASJC Scopus subject areas

  • Microbiology
  • Molecular Medicine
  • Molecular Biology


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