Behavioral stress decreases plasma oxytocin concentrations in primates

Ned H. Kalin, Daniel M. Gibbs, Charles M. Barksdale, Steven E. Shelton, Molly Carnes

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Using rhesus monkeys, we studied the effects of a behavioral stress on plasma concentrations of adrenocorticotropin, oxytocin, and vasopressin. The stress resulted in significant increases in adrenocorticotropin and significant decreases in oxytocin concentrations. No significant changes were seen in vasopressin concentrations. To further explore the relationship between plasma oxytocin and pituitary-adrenal function, dexamethasone was administered to rhesus monkeys. This resulted in significant increases in plasma oxytocin concentrations, while adrenocorticotropin decreased.

Original languageEnglish (US)
Pages (from-to)1275-1280
Number of pages6
JournalLife Sciences
Issue number13
StatePublished - Apr 1 1985
Externally publishedYes

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology


Dive into the research topics of 'Behavioral stress decreases plasma oxytocin concentrations in primates'. Together they form a unique fingerprint.

Cite this