Abstract
Glioma are the most common supra-tentorial brain tumor in the USA with an estimated annual incidence of 17,000 new cases per year. Dynamic susceptibility-weighted contrast-enhanced (DSC) perfusion MRI noninvasively characterizes tumor biology allowing for the diagnosis and therapeutic monitoring of glioma. This MRI technique utilizes the rapid changes in signal intensity caused by a rapid intravascular bolus of paramagnetic contrast agent to calculate physiologic perfusion metrics. DSC perfusion MRI has increasingly become an integrated part of glioma imaging. The specific aim of this article is to review the benefits of DSC perfusion MRI in the therapy of glioma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 407-419 |
| Number of pages | 13 |
| Journal | CNS oncology |
| Volume | 3 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 1 2014 |
| Externally published | Yes |
Keywords
- cerebral blood volume
- dynamic susceptibility-weighted contrast-enhanced perfusion MRI
- glioblastoma
- glioma
- imaging genomics
- metastasis
- molecular imaging
- peak height
- percentage of signal intensity recovery
ASJC Scopus subject areas
- Clinical Neurology
- Neurology