Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI

Ramon Francisco Barajas; Javier Villanueva-Meyer; Arie Perry; Mitchel Berger; Soonmee Cha

doi:10.1016/j.radcr.2017.07.010

Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI

Ramon Francisco Barajas, Javier Villanueva-Meyer, Arie Perry, Mitchel Berger, Soonmee Cha

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.

Original language	English (US)
Pages (from-to)	827-832
Number of pages	6
Journal	Radiology Case Reports
Volume	12
Issue number	4
DOIs	https://doi.org/10.1016/j.radcr.2017.07.010
State	Published - Dec 2017

Keywords

Glioblastoma
Glioma
Image-guided
Spin-lock contrast
T1rho MRI
T1ρ MRI

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.radcr.2017.07.010

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title = "Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI",

abstract = "Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.",

keywords = "Glioblastoma, Glioma, Image-guided, Spin-lock contrast, T1rho MRI, T1ρ MRI",

author = "Barajas, {Ramon Francisco} and Javier Villanueva-Meyer and Arie Perry and Mitchel Berger and Soonmee Cha",

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doi = "10.1016/j.radcr.2017.07.010",

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AU - Barajas, Ramon Francisco

AU - Villanueva-Meyer, Javier

AU - Perry, Arie

AU - Berger, Mitchel

AU - Cha, Soonmee

PY - 2017/12

Y1 - 2017/12

N2 - Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.

AB - Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.

KW - Glioblastoma

KW - Glioma

KW - Image-guided

KW - Spin-lock contrast

KW - T1rho MRI

KW - T1ρ MRI

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Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI

Abstract

Keywords

ASJC Scopus subject areas

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