Botulinum toxin therapy in medical pain disorders

Delaram Safarpour, Bahman Jabbari

Research output: Chapter in Book/Report/Conference proceedingChapter


Animal studies have shown that local injection of botulinum neurotoxins (BoNTs) reduces neuropathic pain. This effect is exerted via interfering with the function of pain transmitters and modulators at peripheral and central levels. Recent studies in humans have demonstrated an analgesic effect in several pain disorders. In this chapter, the effect of BoNT therapy in different medical, human pain syndromes is reviewed. The level of efficacy in each pain syndrome is determined according to the guidelines of the Assessment Subcommittee of the American Academy of Neurology.

Original languageEnglish (US)
Title of host publicationBotulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine
Number of pages26
ISBN (Electronic)9783030506919
ISBN (Print)9783030506902
StatePublished - Oct 6 2020


  • Botulinum neurotoxin
  • Botulinum toxin
  • Neuropathic pain
  • Pain
  • Pain disorder

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Dentistry
  • General Veterinary
  • General Medicine


Dive into the research topics of 'Botulinum toxin therapy in medical pain disorders'. Together they form a unique fingerprint.

Cite this