Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

J. A. Kaye; M. M. Moore; D. Galasko; U. K. Craig; R. Adonay; L. C. Silbert

doi:10.1212/01.wnl.0000265590.66637.e8

Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

J. A. Kaye, M. M. Moore, D. Galasko, U. K. Craig, R. Adonay, L. C. Silbert

Neurology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI brain volumes differed between diagnostic groups (GD, PDC, control) and according to family history. Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders.

Original language	English (US)
Pages (from-to)	196-199
Number of pages	4
Journal	Neurology
Volume	69
Issue number	2
DOIs	https://doi.org/10.1212/01.wnl.0000265590.66637.e8
State	Published - Jul 2007

ASJC Scopus subject areas

Clinical Neurology

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AU - Adonay, R.

AU - Silbert, L. C.

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AB - We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI brain volumes differed between diagnostic groups (GD, PDC, control) and according to family history. Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders.

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Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

Abstract

ASJC Scopus subject areas

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