Breathing Patterns in Recipients of Heart–Lung Transplants

David Systrom; Carlos Fragoso; Nicholas R. Banner; M. Hugh Lloyd; Russell D. Hamilton; Steven A. Shea; J. Alastair Innes; Abraham Guz; Magdi H. Yacoub; Frank C. Sciurba; Gregory R. Owens; Mark H. Sanders; Bartley P. Griffith

doi:10.1056/NEJM198903093201013

Breathing Patterns in Recipients of Heart–Lung Transplants

David Systrom, Carlos Fragoso, Nicholas R. Banner, M. Hugh Lloyd, Russell D. Hamilton, Steven A. Shea, J. Alastair Innes, Abraham Guz, Magdi H. Yacoub, Frank C. Sciurba, Gregory R. Owens, Mark H. Sanders, Bartley P. Griffith

Research output: Contribution to journal › Letter › peer-review

Abstract

To the Editor: The role in humans of pulmonary afferent neuronal pathways in setting the level and pattern of ventilation during exercise has been long debated. Sciurba et al. (Nov. 3 issue)¹ recently found that inspiratory ventilation was depressed at peak exercise in a group of patients whose pulmonary innervation had been interrupted at the time of heart–lung transplantation, when compared with patients who had undergone heart transplantation only. The inspiratory ventilation is directly dependent on carbon dioxide production and the ratio of dead space to tidal volume (Vd/Vt), whereas it is indirectly related to partial pressure of arterial carbon….

Original language	English (US)
Pages (from-to)	669-670
Number of pages	2
Journal	New England Journal of Medicine
Volume	320
Issue number	10
DOIs	https://doi.org/10.1056/NEJM198903093201013
State	Published - Mar 9 1989
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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title = "Breathing Patterns in Recipients of Heart–Lung Transplants",

abstract = "To the Editor: The role in humans of pulmonary afferent neuronal pathways in setting the level and pattern of ventilation during exercise has been long debated. Sciurba et al. (Nov. 3 issue)1 recently found that inspiratory ventilation was depressed at peak exercise in a group of patients whose pulmonary innervation had been interrupted at the time of heart–lung transplantation, when compared with patients who had undergone heart transplantation only. The inspiratory ventilation is directly dependent on carbon dioxide production and the ratio of dead space to tidal volume (Vd/Vt), whereas it is indirectly related to partial pressure of arterial carbon….",

author = "David Systrom and Carlos Fragoso and Banner, {Nicholas R.} and Lloyd, {M. Hugh} and Hamilton, {Russell D.} and Shea, {Steven A.} and Innes, {J. Alastair} and Abraham Guz and Yacoub, {Magdi H.} and Sciurba, {Frank C.} and Owens, {Gregory R.} and Sanders, {Mark H.} and Griffith, {Bartley P.}",

year = "1989",

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doi = "10.1056/NEJM198903093201013",

language = "English (US)",

volume = "320",

pages = "669--670",

journal = "New England Journal of Medicine",

issn = "0028-4793",

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T1 - Breathing Patterns in Recipients of Heart–Lung Transplants

AU - Systrom, David

AU - Fragoso, Carlos

AU - Banner, Nicholas R.

AU - Lloyd, M. Hugh

AU - Hamilton, Russell D.

AU - Shea, Steven A.

AU - Innes, J. Alastair

AU - Guz, Abraham

AU - Yacoub, Magdi H.

AU - Sciurba, Frank C.

AU - Owens, Gregory R.

AU - Sanders, Mark H.

AU - Griffith, Bartley P.

PY - 1989/3/9

Y1 - 1989/3/9

N2 - To the Editor: The role in humans of pulmonary afferent neuronal pathways in setting the level and pattern of ventilation during exercise has been long debated. Sciurba et al. (Nov. 3 issue)1 recently found that inspiratory ventilation was depressed at peak exercise in a group of patients whose pulmonary innervation had been interrupted at the time of heart–lung transplantation, when compared with patients who had undergone heart transplantation only. The inspiratory ventilation is directly dependent on carbon dioxide production and the ratio of dead space to tidal volume (Vd/Vt), whereas it is indirectly related to partial pressure of arterial carbon….

AB - To the Editor: The role in humans of pulmonary afferent neuronal pathways in setting the level and pattern of ventilation during exercise has been long debated. Sciurba et al. (Nov. 3 issue)1 recently found that inspiratory ventilation was depressed at peak exercise in a group of patients whose pulmonary innervation had been interrupted at the time of heart–lung transplantation, when compared with patients who had undergone heart transplantation only. The inspiratory ventilation is directly dependent on carbon dioxide production and the ratio of dead space to tidal volume (Vd/Vt), whereas it is indirectly related to partial pressure of arterial carbon….

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Breathing Patterns in Recipients of Heart–Lung Transplants

Abstract

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