The neuropathology of the encephalopathy of prematurity (see Chapter 14) includes injury to cerebral white matter and, in a major proportion of infants, a variety of neuronal-axonal disturbances. The encephalopathy includes a broad spectrum of initiating destructive events or disturbances in cellular maturation that are followed by widespread disruptions in cerebral white and gray matter growth and neuronal connectivity. This chapter emphasizes the pathophysiology of the most consistent and well-defined feature of the encephalopathy, injury to the cerebral white matter.
|Original language||English (US)|
|Title of host publication||Volpe's Neurology of the Newborn|
|State||Published - Jan 1 2018|
- cerebral blood flow
- maternal-fetal infection
ASJC Scopus subject areas