CFTR: New Members Join the Fold

William R. Skach

Research output: Contribution to journalShort surveypeer-review

23 Scopus citations


The folding, misfolding, and degradation of membrane proteins is controlled by multiple processes within the cell. In this issue of Cell, Wang et al. (2006) present an interactome for CFTR, the chloride channel that is misfolded and prematurely degraded in cystic fibrosis. Among the proteins interacting with CFTR is a new member of the Hsp90 chaperone system, Aha1, that plays a central role in CFTR folding.

Original languageEnglish (US)
Pages (from-to)673-675
Number of pages3
Issue number4
StatePublished - Nov 17 2006
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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