Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy

Marian L. Dale; Deniz Erten-Lyons; Frank Bittner; Randy Woltjer

doi:10.1136/bcr-2018-227119

Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy

Marian L. Dale, Deniz Erten-Lyons, Frank Bittner, Randy Woltjer

Research output: Contribution to journal › Article › peer-review

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Abstract

We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue.

Original language	English (US)
Article number	e227119
Journal	BMJ Case Reports
Volume	11
Issue number	1
DOIs	https://doi.org/10.1136/bcr-2018-227119
State	Published - Nov 1 2018

ASJC Scopus subject areas

Medicine(all)

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abstract = "We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue.",

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AU - Erten-Lyons, Deniz

AU - Bittner, Frank

AU - Woltjer, Randy

N1 - Publisher Copyright: © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue.

AB - We report a case of a progressive supranuclear palsy-like phenotype with rapidly progressive dementia and prominent language and executive dysfunction. Pathological examination revealed no midbrain or white matter tauopathy, but rather chronic meningoencephalitis and other mixed pathology. The cerebrospinal fluid (CSF) in this case showed a novel antibody against central nervous system and renal tissue.

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Chronic meningoencephalitis with mixed pathology mimics progressive supranuclear palsy

Abstract

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