Clinical guidelines for intraspinal infusion: Report of an expert panel

Gary Bennett, Kim Burchiel, Eric Buchser, Ashley Classen, Tim Deer, Stuart Du Pen, F. Michael Ferrante, Samuel J. Hassenbusch, Leland Lou, Jan Maeyaert, Richard Penn, Russell K. Portenoy, Richard Rauck, Mario Serafini, K. Dean Willis, Tony Yaksh

Research output: Contribution to journalArticlepeer-review

140 Scopus citations


Consensus guidelines developed by an expert panel are helpful to clinicians when there is variation in practice and lack of a firm evidence base for an intervention, such as intraspinal therapy for pain. An internet- based survey of practitioners revealed remarkable variation in practice patterns surrounding intraspinal therapy. This prompted an interdisciplinary panel with extensive clinical experience in intraspinal infusion therapy to evaluate the results of the survey, the systematic reviews of the literature pertaining to this approach, and their own clinical experience with long-term spinal infusions. The panel proposed a scheme for the selection of drugs and doses for intraspinal therapy, and suggested guidelines for administration that would increase the likelihood of a successful outcome. These expert panel guidelines were designed to provide an initial structure for clinical decision making that is based on the best available evidence and the perspectives of experienced clinicians. (C) U.S. Cancer Pain Relief Committee, 2000.

Original languageEnglish (US)
Pages (from-to)S37-S43
JournalJournal of Pain and Symptom Management
Issue number2
StatePublished - Aug 2000


  • Clinical practice
  • Decision making
  • Guidelines
  • Intraspinal therapy
  • Intrathecal

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


Dive into the research topics of 'Clinical guidelines for intraspinal infusion: Report of an expert panel'. Together they form a unique fingerprint.

Cite this