Clinicopathologic variants of cutaneous squamous cell carcinoma

Christina M. Lohmann, Alvin R. Solomon

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


Cutaneous squamous cell carcinomas (SCC) are one of the most common malignancies, which, with early recognition, may be curable. These tumors represent a broad spectrum of disorders with many significant clinical, morphologic, and etiologic distinctions. The objective of this article is to review the important clinicopathologic features of SCC with particular emphasis on important recent developments, practical application, and their relevance to the practice of pathology. The most pertinent literature of the last 5 years was reviewed and capsulized. Appropriate histologic interpretation and clinical management of patients with cutaneous SCC requires a comprehensive understanding of the latest advances in the broad field of dermatopathology. Squamous cell carcinoma of the skin represents a complex group of disease subtypes, each with its own characteristics, which may influence morphologic diagnosis as well as treatment and clinical management.

Original languageEnglish (US)
Pages (from-to)27-36
Number of pages10
JournalAdvances in Anatomic Pathology
Issue number1
StatePublished - Jan 2001
Externally publishedYes


  • Cutaneous malignancy
  • Skin cancer
  • Skin tumor
  • Squamous cell carcinoma (SCC)

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine


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